The ability of sonographic cervical length screening to detect those at risk of spontaneous
preterm delivery has been extensively explored over the past few years. This applies both to …

Background A sonographic short cervix (length< 25 mm during midgestation) is the most
powerful predictor of preterm birth. Current clinical practice assumes that the same cervical …

Background Precocious cervical ripening, as defined by cervical shortening on transvaginal
sonography, has prompted a broad evaluation of secondary strategies (such as cerclage …

Objective To investigate the efficacy of vaginal progesterone to prevent early preterm birth in
women with sonographic evidence of a short cervical length in the midtrimester. Methods …

OBJECTIVE: We sought to provide evidence-based guidelines for using progestogens for
the prevention of preterm birth (PTB). METHODS: Relevant documents, in particular …

OBJECTIVE: We sought to evaluate 17-alpha-hydroxyprogesterone caproate (17P) for
prevention of preterm birth (PTB) in women with prior spontaneous PTB (SPTB) and cervical …

In this issue of the Journal, Romero et al 1 report the results of an individual patient data
(IPD) meta-analysis on the use of daily vaginal progesterone in women with a midtrimester …

Objectives To determine whether progesterone supplementation alters cervical shortening
in women at increased risk for preterm birth. Methods We performed a planned secondary …

Progestogens are the first drugs to demonstrate reproducibly a reduction in the rate of early
preterm birth. The efficacy and safety of progestogens are related to individual …

OBJECTIVE: To compare the effectiveness of a cervical pessary and vaginal progesterone
to prevent spontaneous preterm births in pregnant women with cervical lengths 25 mm or …