Cancer is a complex disease affecting millions of people around the world. Despite
advances in surgical and radiation therapy, chemotherapy continues to be an important …

Drug repurposing is a strategy that seeks new medical treatments from existing licensed
medications rather than from de novo development of new molecules. The rationale for this …

While majority of the current treatment approaches for cancer remain expensive and are
associated with several side effects, development of new treatment modalities takes a …

Despite huge efforts made in academic and pharmaceutical worldwide research, current
anticancer therapies achieve effective treatment in a limited number of neoplasia cases only …

Drug repurposing for cancer therapy is currently a hot topic of research. Theoretically, in
contrast to the known hurdles of developing new molecular entities, the approach of …

Ongoing new insights in the field of cancer diagnostics, genomic profiling, and cancer
behavior have raised the demand for novel, personalized cancer treatments. As the …

Background Drug repurposing can speed up access to new therapeutic options for cancer
patients. With more than 2000 drugs approved worldwide and 6 relevant targets per drug on …

Drug repurposing is at the heart of precision oncology. The move from tissue-or cancer-
specific treatments to genomic-or actionable-target treatments necessarily entails the reuse …

Schematic diagram depicting the major approaches to facilitate drug repurposing for
precision oncology.(1) In silico prediction to establish drug-target associations according to …

Cancer, a complex and multifactorial disease, presents a significant challenge to global
health. Despite significant advances in surgical, radiotherapeutic and immunological …