We examined 1) whether global cerebral blood flow (CBF) would increase across a 6-h bout
of normobaric poikilocapnic hypoxia and be mediated by a larger increase in blood flow in …

We examined the impact of progressive hypotension with and without hypocapnia on
regional extracranial cerebral blood flow (CBF) and intracranial velocities. Participants …

The inability to quantify cerebral blood flow and changes in macrocirculation cross-sectional
area in all brain regions impedes robust insight into hypoxic cerebral blood flow control. We …

New Findings• What is the central question of this study? Does hypoxia enhance blood flow
to all parts of the brain uniformly?• What is the main finding and its importance? During …

Acute hypoxia directly causes cerebral arteriole vasodilation and also stimulates peripheral
chemoreceptors to change autonomic neural activity. These changes may alter cerebral …

Key points Cognitive performance is impaired by hypoxia despite global cerebral oxygen
delivery and metabolism being maintained. Using arterial spin labelled (ASL) magnetic …

The brain is a vital organ that relies on a constant and adequate supply of blood to match
oxygen and glucose delivery with the local metabolic demands of active neurones. It is well …

Aim: Acute hypobaric hypoxia is well known to alter brain circulation and to cause
neuropsychological impairment. However, very few studies have examined the regional …

Single Photon Emission Computed Tomography (SPECT) and radiopharmaceutical
stabilizing agents allowed us to investigate regional cerebral blood flow (CBF) distribution in …

The role of the sympathetic nervous system in cerebral blood flow (CBF) regulation remains
unclear. Previous studies have primarily measured middle cerebral artery blood velocity to …