Utilizing micro-X-ray CT (μCT) imaging, we sought to generate an atlas of in vivo and
intact/ex vivo lungs from normal murine strains. In vivo imaging allows visualization of …

Imaging of targeted fluorescent probes offers significant advantages for investigating
disease and tissue function in animal models in vivo. Conversely, macroscopic tomographic …

Obstructive, interstitial, infectious and malignant lung diseases remain among the most
important health challenges and novel or improved therapeutic strategies are essential for …

Metastasis to secondary sites such as the lung, liver and bone is a traumatic event with a
mortality rate of approximately 90% 1. Of these sites, the lung is the most difficult to assess …

Introduction: Asthma is a global burden, affecting 5% of the general adult population, with
approximately 5–10% suffering from severe asthma. Severe asthma is a complex …

The advent of micro-computed tomography (microCT) has provided significant advancement
in our ability to generate clinically relevant assessments of lung health and disease in small …

Bioluminescence refers to the process of visible light emission in living organisms.
Bioluminescence imaging is a powerful methodology that has been developed over the last …

Objective Accurate imaging biomarkers that indicate disease progression at an early stage
are highly important to enable timely mitigation of symptoms in progressive lung disease. In …

Advances in characterization of molecular and genomic abnormalities specific to lung
cancer have made precision therapy the current standard of care for lung cancer treatment …

The global increase in asthma, chronic obstructive pulmonary disease, and other pulmonary
diseases has stimulated interest in preclinical rat models of pulmonary disease. Imaging …