Animal models of pulmonary inflammation are critical for understanding the pathophysiology
of asthma and for developing new therapies. Current conventional assessments in mouse …

This review presents an overview of some recent magnetic resonance imaging (MRI)
techniques for measuring aspects of local physiology in the lung. MRI is noninvasive …

Intravital microscopy has been recognized for its ability to make physiological
measurements at cellular and subcellular levels while maintaining the complex natural …

The delicate structure of murine lungs poses many challenges for acquiring high-quality
images that truly represent the living lung. Here, we describe several optimized procedures …

Before microcomputed tomography (micro-CT) can be exploited to its full potential for
longitudinal monitoring of transgenic and experimental mouse models of lung diseases …

The balance of lung extravascular water depends upon the control of blood flow in the
alveolar distribution vessels that feed downstream two districts placed in parallel, the corner …

Purpose: Small animal micro‐CT imaging is being used increasingly in preclinical
biomedical research to provide phenotypic descriptions of genomic models. Most of this …

Physiological conditions and pathophysiological changes in the lungs may affect many
applications in aerosol medicine and pulmonary drug delivery. In the diseased lung, spatial …

Stereology is the method of choice for the quantitative assessment of biological objects in
microscopy. It takes into account the fact that, in traditional microscopy such as conventional …

Byproducts of cellular respiration, including carbon dioxide, must be removed from cells
immediately, through the circulation and finally to the outside of the body via the respiratory …