[HTML][HTML] Genetic risk scores for body fat distribution attenuate weight loss in women during dietary intervention

M Svendstrup, KH Allin, TIA Sørensen… - International Journal of …, 2018 - nature.com
Objective: The well-established link between body fat distribution and metabolic health has
been suggested to act through an impact on the remodeling capacity of the adipose tissue …

Genetic determination of body fat distribution and the attributive influence on metabolism

E Fehlert, R Wagner, C Ketterer, A Böhm, J Machann… - …, 2017 - Wiley Online Library
Objective Genome‐wide association studies (GWAS) have identified single‐nucleotide
polymorphisms (SNPs) associated with estimates of body fat distribution. Using predefined …

[HTML][HTML] Distinct genetic subtypes of adiposity and glycemic changes in response to weight-loss diet intervention: the POUNDS Lost trial

Y Chen, T Zhou, D Sun, X Li, H Ma, Z Liang… - European journal of …, 2021 - Springer
Purpose Obesity is a heterogeneous condition and distinct adiposity subtypes may
differentially affect type 2 diabetes risk. We assessed relations between genetically …

Impact of genetic variants on the individual potential for body fat loss

S Cha, JH Kang, JH Lee, J Kim, H Kim, YJ Yang… - Nutrients, 2018 - mdpi.com
The past decade has witnessed the discovery of obesity-related genetic variants and their
functions through genome-wide association studies. Combinations of risk alleles can …

Genetic predictors of weight loss in overweight and obese subjects

I Lamiquiz-Moneo, R Mateo-Gallego, AM Bea… - Scientific reports, 2019 - nature.com
The aim of our study was to investigate a large cohort of overweight subjects consuming a
homogeneous diet to identify the genetic factors associated with weight loss that could be …

Interaction of genetic and environmental factors for body fat mass control: observational study for lifestyle modification and genotyping

JH Kang, H Kim, J Kim, JH Seo, S Cha, H Oh, K Kim… - Scientific Reports, 2021 - nature.com
Previous studies suggested that genetic, environmental factors and their interactions could
affect body fat mass (BFM). However, studies describing these effects were performed at a …

Association of genetic variants related to gluteofemoral vs abdominal fat distribution with type 2 diabetes, coronary disease, and cardiovascular risk factors

LA Lotta, LBL Wittemans, V Zuber, ID Stewart, SJ Sharp… - Jama, 2018 - jamanetwork.com
Importance Body fat distribution, usually measured using waist-to-hip ratio (WHR), is an
important contributor to cardiometabolic disease independent of body mass index (BMI) …

Genetic predictors of change in waist circumference and waist-to-hip ratio with lifestyle intervention: The trans-nih consortium for genetics of weight loss response to …

JM McCaffery, KA Jablonski, Q Pan, A Astrup… - Diabetes, 2022 - Am Diabetes Assoc
Genome-wide association studies have identified single nucleotide polymorphisms (SNPs)
associated with waist circumference (WC) and waist-to-hip ratio (WHR) adjusted for BMI …

Relationships between body fat distribution and metabolic syndrome traits and outcomes: A mendelian randomization study

B Huang, J DePaolo, RL Judy, G Shakt, WR Witschey… - Plos one, 2023 - journals.plos.org
Background Obesity is a complex, multifactorial disease associated with substantial
morbidity and mortality worldwide. Although it is frequently assessed using BMI, many …

Effects of obesity related genetic variations on visceral and subcutaneous fat distribution in a Chinese population

T Wang, X Ma, D Peng, R Zhang, X Sun, M Chen… - Scientific reports, 2016 - nature.com
Genome-wide association studies (GWAS) have uncovered numerous variants associated
with body mass index (BMI), waist circumference, and waist-to-hip ratio. Our study aims to …