[HTML][HTML] Neuroinflammation in Parkinson's disease and its potential as therapeutic target

Q Wang, Y Liu, J Zhou - Translational neurodegeneration, 2015 - Springer
Abstract Parkinson's disease (PD), the second most common age-associated
neurodegenerative disorder, is characterized by the loss of dopaminergic (DA) neurons and …

[HTML][HTML] Neuroinflammation in Parkinson's disease–putative pathomechanisms and targets for disease-modification

A Grotemeyer, RL McFleder, J Wu… - Frontiers in …, 2022 - frontiersin.org
Parkinson's disease (PD) is a progressive and debilitating chronic disease that affects more
than six million people worldwide, with rising prevalence. The hallmarks of PD are motor …

Updates on immunity and inflammation in Parkinson disease pathology

N Joshi, S Singh - Journal of neuroscience research, 2018 - Wiley Online Library
Studies in the last decade have suggested the association of both neuroinflammatory
processes and immune responses in Parkinson disease (PD) pathology. PD pathology is …

Evidence of inflammatory system involvement in Parkinson's disease

Y Chao, SC Wong, EK Tan - BioMed research international, 2014 - Wiley Online Library
Parkinson's disease (PD) is a chronic neurodegenerative disease underpinned by both
genetic and environmental etiologic factors. Recent findings suggest that inflammation may …

Neuroinflammation is a key player in Parkinson's disease and a prime target for therapy

L Qian, PM Flood, JS Hong - Journal of neural transmission, 2010 - Springer
Parkinson's disease (PD) is a neurodegenerative movement disorder characterized by the
progressive loss of dopaminergic neurons in the substantia nigra and depletion of dopamine …

[HTML][HTML] Neuroinflammation and Parkinson's disease—From neurodegeneration to therapeutic opportunities

B Araújo, R Caridade-Silva, C Soares-Guedes… - Cells, 2022 - mdpi.com
Parkinson's disease (PD) is the second most prevalent neurodegenerative disorder
worldwide. Clinically, it is characterized by a progressive degeneration of dopaminergic …

[HTML][HTML] Neurodegeneration and neuroinflammation in Parkinson's disease: a self-sustained loop

G Arena, K Sharma, G Agyeah, R Krüger… - Current Neurology and …, 2022 - Springer
Abstract Purpose of Review Neuroinflammation plays a significant role in Parkinson's
disease (PD) etiology along with mitochondrial dysfunction and impaired proteostasis. In this …

Neuroinflammation in Parkinson's disease: triggers, mechanisms, and immunotherapies

T Wang, C Shi, H Luo, H Zheng, L Fan… - The …, 2022 - journals.sagepub.com
Parkinson's disease (PD) is a heterogeneous neurodegenerative disease involving multiple
etiologies and pathogenesis, in which neuroinflammation is a common factor. Both …

[HTML][HTML] Inflammation in Parkinson's disease: mechanisms and therapeutic implications

M Pajares, A I. Rojo, G Manda, L Boscá, A Cuadrado - Cells, 2020 - mdpi.com
Parkinson's disease (PD) is a common neurodegenerative disorder primarily characterized
by the death of dopaminergic neurons that project from the substantia nigra pars compacta …

Immune responses in Parkinson's disease: interplay between central and peripheral immune systems

X Su, HJ Federoff - BioMed research international, 2014 - Wiley Online Library
The etiology of Parkinson's disease (PD) is complex and most likely involves numerous
environmental and heritable risk factors. Recent studies establish that central and peripheral …