Mechanisms of amiodarone pulmonary toxicity

WJ Martin II - Clinics in chest medicine, 1990 - Elsevier
Amiodarone pulmonary toxicity is one of the most important examples of drug-induced lung
disease by non-cancer chemotherapeutic agents. Current concepts suggest that patients …

Amiodarone-induced pulmonary toxicity: predisposing factors, clinical symptoms and treatment

GAJ Jessurun, WG Boersma, HJGM Crijns - Drug Safety, 1998 - Springer
Amiodarone is frequently used for the treatment of cardiac arrhythmias. Although the
therapeutic efficacy of amiodarone has been established, its use is limited by its safety …

Amiodarone pulmonary toxicity: clinical and subclinical features

PC Adams, GJ Gibson, AR Morley… - … Journal of Medicine, 1986 - academic.oup.com
In a prospective study of lung function of 34 patients taking amiodarone, 24 showed no
functional changes but 10 developed a sustained fall in CO transfer factor (TLCO) exceeding …

Amiodarone: review of pulmonary effects and toxicity

SA Papiris, C Triantafillidou, L Kolilekas, D Markoulaki… - Drug safety, 2010 - Springer
Amiodarone, a bi-iodinated benzofuran derivative, is, because of its high effectiveness, one
of the most widely used antiarrhythmic agents. However, adverse effects, especially …

Amiodarone-induced pulmonary toxicity: an under-recognized and severe adverse effect?

M Schwaiblmair, T Berghaus, T Haeckel… - Clinical Research in …, 2010 - Springer
Several forms of pulmonary disease occur among patients treated with amiodarone, ie
chronic interstitial pneumonitis, organizing pneumonia, ARDS, a solitary pulmonary mass of …

Amiodarone pulmonary toxicity: morphologic and biochemical features

MJ Reasor, S Kacew - Proceedings of the Society for …, 1991 - journals.sagepub.com
Conclusions Since the discovery of amiodarone over 30 years ago, the mechanisms
underlying serious adverse effects remain to be resolved and still limit drug usefulness …

[引用][C] Pulmonary complications of amiodarone toxicity

M Dunn, J Glassroth - Progress in cardiovascular diseases, 1989 - Elsevier
HYDROCHLORIDE, a benzofurone derivative, has been used since 1969 for the control of
cardiac arrhythmias in the United States. It appears to be uniquely effective for some patients …

Amiodarone pulmonary toxicity: a multidisciplinary review of current status.

AE Fraire, KK Guntupalli, SD Greenberg… - Southern medical …, 1993 - europepmc.org
Amiodarone, a benzofuran derivative, has proven useful in the control of serious cardiac
arrhythmias. We reviewed the English language medical literature to characterize clinical …

Acute amiodarone-induced pulmonary toxicity following lung resection

AE Handschin, D Lardinois, D Schneiter, K Bloch… - Respiration, 2003 - karger.com
Amiodarone-induced pulmonary toxicity has been described mostly in patients receiving
large doses of the drug over prolonged periods. In this report, we describe the early onset of …

Amiodarone-induced pneumonitis: assessment of risk factors and possible risk reduction

GD Adams, R Kehoe, M Lesch, J Glassroth - Chest, 1988 - Elsevier
Problems with pulmonary toxicity have emerged as a potentially limiting factor for
amiodarone use. We prospectively studied 33 subjects treated with amiodarone for …