In recent decades, many fungal species have emerged as major causes of human disease.
While invasive candidiasis, aspergillosis, and cryptococcosis remain very common, rates of …

Fungal diseases became a major medical problem in the second half of the 20th century
when advances in modern medicine together with the HIV epidemic resulted in large …

Localized and systemic fungal infections caused by Candida albicans can lead to significant
mortality and morbidity. However, severe C. albicans infections are relatively rare, occurring …

Many human fungal pathogens are opportunistic. They are primarily benign residents of the
human body and only become infectious when the host's immunity and microbiome are …

Environmental fungi are globally ubiquitous and human exposure is near universal.
However, relatively few fungal species are capable of infecting humans, and among fungi …

Fungi cover epithelial surfaces of the human body, engaging in many mutualistic
interactions with the host and other microbiota such as the more prevalent bacteria. These …

Few among the millions of fungal species fulfill four basic conditions necessary to infect
humans: high temperature tolerance, ability to invade the human host, lysis and absorption …

The frequency of invasive mycoses due to opportunistic fungal pathogens has increased
significantly over the past two decades (35, 74, 83, 88, 89, 101, 106). This increase in …

Highlights•The immune system is constantly exposed to fungi living at host mucosal surfaces
or coming from the environment.•Interactions between fungi and host immunity have …

Morphological changes are a very common and effective strategy for pathogens to survive in
the mammalian host. During interactions with their host, human pathogenic fungi undergo …