Accelerated development of novel CRISPR/Cas9-based genome editing techniques
provides a feasible approach to introduce a variety of precise modifications in the …

The CRISPR/Cas9 system has been adapted as an efficient genome editing tool in
laboratory animals such as mice, rats, zebrafish and pigs. Here, we report that …

In recent years, significant progress has been achieved in genome editing applications
using new programmable DNA nucleases such as zinc finger nucleases (ZFNs) …

Humans are sorely over-dependent on livestock for their daily basic need of food in the form
of meat, milk, and eggs. Therefore, genetic engineering and transgenesis provide the …

CRISPR/Cas9 system genome editing is revolutionizing genetics research in a wide
spectrum of animal models in the genetic era. Among these animals, is the poultry species …

Background The simplicity of the CRISPR/Cas9 system has enabled its widespread
applications in generating animal models, functional genomic screening and in treating …

The sophistication and revolution in genome editing and manipulation have revolutionized
livestock by harvesting essential biotechnological products such as drugs, proteins, and …

In recent years, genome engineering technology has provided unprecedented opportunities
for site-specific modification of biological genomes. Clustered regularly interspaced short …

The CRISPR/Cas9 genome editing tool has the potential to improve the livestock breeding
industry by allowing for the introduction of desirable traits. Although an efficient and targeted …

Contents Genome modification at specific loci in livestock species was only achievable by
performing homologous recombination in somatic cells followed by somatic cell nuclear …