The MYC oncogene has been implicated in the regulation of up to thousands of genes
involved in many cellular programs including proliferation, growth, differentiation, self …

Deregulated expression of the Myc transcription factor is a frequent causal mutation in
human cancer. Thousands of putative Myc target genes have been identified in in vitro …

MYC overexpression has been implicated in the pathogenesis of most types of human
cancers. MYC is likely to contribute to tumorigenesis by its effects on global gene …

MYC proto-oncogenes play a major role in various types of human tumors. The products of
these genes are transcription factors that bind to specific sequences and activate the …

The c-myc proto-oncogene can direct a diverse array of biological activities, including cell
cycle progression, apoptosis, and differentiation. It is believed that Myc can affect this wide …

The myc proto-oncogenes encode transcriptional regulators whose inappropriate
expression is correlated with a wide array of human malignancies. Up-regulation of Myc …

Mammalian c-Myc is a member of a small family of three related proto-oncogenic
transcription factors. c-Myc has an unusually broad array of regulatory functions, which …

MYC affects normal and neoplastic cell proliferation by altering gene expression, but the
precise pathways remain unclear. We used oligonucleotide microarray analysis of 6,416 …

The proto-oncogene c-myc (myc) encodes a transcription factor (Myc) that promotes growth,
proliferation and apoptosis. Myc has been suggested to induce these effects by …

The functions of key oncogenic transcription factors independent of context have not been
fully delineated despite our richer understanding of the genetic alterations in human …