Cerebral blood flow (CBF) and its distribution are highly sensitive to changes in the partial
pressure of arterial CO2 (PaCO2). This physiological response, termed cerebrovascular …

This study examined cerebrovascular reactivity and ventilation during step changes in CO2
in humans. We hypothesized that:(1) end‐tidal P (P) would overestimate arterial P (P) during …

This study characterized cerebral blood flow (CBF) responses in the middle cerebral artery
to P CO2ranging from 30 to 60 mmHg (1 mmHg= 133.322 Pa) during hypoxia (50 mmHg) …

Indomethacin (INDO), a reversible cyclooxygenase inhibitor, is a useful tool for assessing
the role of cerebrovascular reactivity on ventilatory control. Despite this, the effect of INDO on …

1 Under conditions of both euoxia and hypoxia, it is generally accepted that the ventilatory
response to CO2 has both rapid (peripheral chemoreflex) and slow (central chemoreflex) …

Rationale: Cerebrovascular reactivity to CO2 provides an important counterregulatory
mechanism that serves to minimize the change in H+ at the central chemoreceptor, thereby …

We used rebreathing with prior hyperventilation to measure ventilatory responses to CO2 at
iso-oxic PO2's of 100, 80, 60 and 40 mmHg in seven subjects. The mean sub-threshold …

We tested the hypothesis that hyperthermic hyperventilation in part reflects enhanced
chemoreceptor ventilatory O2 drive, and that the resultant hypocapnia attenuates ventilatory …

We examined changes in the blood flow velocity of brain stem artery (BSA) and middle
cerebral artery (MCA) in response to hypercapnic, normocapnic and hypocapnic …

The purpose of this study was to quantify the possible reduction in ventilation that could be
attributed to changes in cerebral blood flow (CBF) with hypoxia to determine whether it could …