Background Several studies have suggested that after regular use of short acting β2‐
agonists the bronchodilator effect of the drug may decline and this condition would be …

The beta2-adrenergic receptor (beta2AR) agonists are the most widely used agents in the
treatment of asthma, but the genetic determinants of responsiveness to these agents are …

Background: Regular use of inhaled β-adrenergic agonists may have adverse effects in
some asthma patients. Polymorphisms of the β2-adrenergic receptor (β2-AR) can affect its …

BACKGROUND: New evidence suggests that different β2-adrenergic receptor (β2AR)
polymorphisms may influence asthma control in patients receiving long-acting β2-agonists …

The aim of this study was to determine the influence of single nucleotide polymorphisms in
the β2-adrenoceptor gene, on the response to inhaled β2-agonists in children with acute …

Inhaled β-adrenergic agonists are the most commonly used medications for the treatment of
asthma although there is evidence that regular use may produce adverse effects in some …

Rationale: Genetic variation of the β2-adrenoceptor (ADRB2) influences receptor function in
vitro. There are reports that, in vivo, bronchodilator response is related to ADRB2 genotype …

Background. About 9% of children have asthma, corresponding to almost 6.8 million
children in the USA and 1.1 million in the UK. Asthma exacerbations are the leading cause …

Background The β 2-adrenergic receptor gene is one of the most extensively studied genes
with respect to asthma prevalence and severity. The Arg16Gly and Gln27Glu polymorphisms …

Background With β‐agonists being the most widely used agents in the treatment of asthma,
in vitro studies reported that β2‐adrenergic receptor (ADRB2) polymorphisms are …