The aim of the present study was to investigate the expression and signaling of the G protein-
coupled estrogen receptor 1 (GPER) in cultured immature rat Sertoli cells—in which we …

The aim of the present study was to determine the mechanisms involved in estrogen actions
in cultured rat Sertoli cells. RT-PCR detected transcripts for the estrogen receptors ESR1 …

The aim of the present study was to investigate the intracellular signaling events
downstream of the classical estrogen receptors (ESRs) and G protein-coupled estrogen …

Background Estrogen signaling is mediated by estrogen receptor beta isoforms in normal
and neoplastic human testes. Recently, a G-protein-coupled-receptor (GPER) has been …

Estrogen signaling is considered to play an important role in spermatogenesis,
spermiogenesis and male fertility. Estrogens can act via the two nuclear estrogen receptors …

Many studies have indicated that estrogens could have a role in the regulation of testicular
function. However, it remains uncertain whether estrogens are able to directly activate …

Estrogens play important roles in the regulation of testis development and spermatogenesis.
Moreover, several evidences suggest that estrogen signaling can be involved in testicular …

Purpose Estradiol (E2) modulates testicular functions including steroidogenesis, but the
mechanisms of E2 signaling in human testis are poorly understood. GPER-1 (GPR30), a G …

Besides the two nuclear oestrogen receptors (ESR 1/ESR 2), the G protein‐coupled
oestrogen receptor (GPER) was described in the human testis but little is known about …

In this study, G-coupled estrogen receptor (GPER) was inactivated, by treatment with
antagonist (G-15), in testes of C57BL/6 mice: immature (3 weeks old), mature (3 months old) …