Intrauterine infection and inflammation are major reasons for preterm birth. The switch from
placenta-mediated to lung-mediated oxygen supply during birth is associated with a sudden …

Aims Maternal inflammation is a risk factor for preterm birth, and premature infants are often
exposed to supplemental oxygen as a life-sustaining therapy. While more immature …

Little is known about roles of inflammation and hypoxic ischemia (HI) in the generation of
neuroinflammation and damage of blood-brain barrier (BBB) in the white matter (WM) that …

Hypoxic exposure in the perinatal period causes periventricular white matter damage
(PWMD), a condition associated with myelination abnormalities. Under hypoxic conditions …

Background Perinatal asphyxia and exposure to intrauterine infection are associated with
impaired neurodevelopment in preterm infants. Acute exposure to non-injurious infection …

Hypoxic‐ischaemic episodes experienced at the perinatal period commonly lead to a
development of neurological disabilities and cognitive impairments in neonates or later in …

Antenatal inflammation is associated with increased severity of hypoxic-ischemic (HI)
encephalopathy and adverse outcome in human neonates and experimental rodents. We …

Background Infants born preterm commonly suffer from a combination of hypoxia-ischemia
(HI) and infectious perinatal inflammatory insults that lead to cerebral palsy, cognitive delay …

Impaired neurological development in premature infants frequently arises from
periventricular white matter injury (PWMI), a condition associated with myelination …

White matter disease in preterm infants comes along with focal destructions or with diffuse
myelination disturbance. Recent experimental work with transgenic mice paves the way for a …