A validated composite comorbidity index predicts outcomes of CAR T-cell therapy in patients with diffuse large B-cell lymphoma

G Shouse, A Kaempf, MJ Gordon, A Artz… - Blood …, 2023 - ashpublications.org
Chimeric antigen receptor T-cell therapy (CART) has extended survival of patients with
relapsed/refractory diffuse large B-cell lymphoma (DLBCL). However, limited durability of …

[HTML][HTML] Comorbidities predict inferior survival in patients receiving chimeric antigen receptor T cell therapy for diffuse large B cell lymphoma: a multicenter analysis

AS Kittai, Y Huang, M Gordon, N Denlinger… - … and Cellular Therapy, 2021 - Elsevier
Chimeric antigen receptor T cell (CAR-T) therapy is approved for treatment of
relapsed/refractory (R/R) diffuse large B cell lymphoma (DLBCL). Here we evaluate whether …

[HTML][HTML] Overcoming barriers to referral for chimeric antigen receptor T cell therapy in patients with relapsed/refractory diffuse large B cell lymphoma

MS Hoffmann, BD Hunter, PW Cobb, JC Varela… - … and Cellular Therapy, 2023 - Elsevier
Diffuse large B cell lymphoma (DLBCL) is the most prevalent subtype of non-Hodgkin
lymphoma. Although outcomes to frontline therapy are encouraging, patients who are …

[HTML][HTML] The International Prognostic Index is associated with outcomes in diffuse large B cell lymphoma after chimeric antigen receptor T cell therapy

M Garcia-Recio, K Wudhikarn, M Pennisi… - … and cellular therapy, 2021 - Elsevier
ABSTRACT CD19-targeted chimeric antigen receptor (CAR) T cells have shown excellent
activity against relapsed and refractory (R/R) diffuse large B cell lymphoma (DLBCL). CAR T …

Predictive factors of early progression after CAR T-cell therapy in relapsed/refractory diffuse large B-cell lymphoma

L Vercellino, R Di Blasi, S Kanoun, B Tessoulin… - Blood …, 2020 - ashpublications.org
Chimeric antigen receptor (CAR) T-cell therapy has emerged as an option for
relapsed/refractory aggressive B-cell lymphomas that have failed 2 lines of therapy. Failures …

Chimeric antigen receptor T‐cell therapy combined with autologous stem cell transplantation improved progression‐free survival of relapsed or refractory diffuse large …

T Wang, L Xu, L Gao, G Tang, L Chen… - Hematological …, 2022 - Wiley Online Library
Autologous hematopoietic stem cell transplantation (ASCT) and chimeric antigen receptor T‐
cell therapy (CART) are salvage therapies that are utilised for treatment of relapsed or …

[HTML][HTML] Patient perspectives on health-related quality of life in diffuse large B-cell lymphoma treated with Car T-cell therapy: a qualitative study

R Cheng, K Scippa, FL Locke, JT Snider, H Jim - Oncology and Therapy, 2022 - Springer
Introduction Chimeric antigen receptor T-cell (CAR T) therapy offers a potentially curative
option for patients with relapsed and refractory hematologic malignancies, including diffuse …

Outcomes in patients with DLBCL treated with commercial CAR T cells compared with alternate therapies

D Sermer, C Batlevi, ML Palomba, G Shah… - Blood …, 2020 - ashpublications.org
The prognosis of patients with relapsed or refractory (R/R) diffuse large B-cell lymphoma
(DLBCL) is poor. Chimeric antigen receptor (CAR) T-cell therapy has been approved for R/R …

[HTML][HTML] Cellular immunotherapy for refractory diffuse large B cell lymphoma in the chimeric antigen receptor-engineered T cell era: still a role for allogeneic …

P Dreger, TS Fenske, S Montoto, MC Pasquini… - Biology of Blood and …, 2020 - Elsevier
Chimeric antigen receptor-engineered T (CART) cells are a promising new treatment option
for patients with multiply relapsed and refractory (R/R) diffuse large B cell lymphoma …

[HTML][HTML] ASTCT committee on practice guidelines survey on evaluation & management of diffuse large b-cell lymphoma after failure of chimeric antigen receptor t cell …

N Ahmed, A Kumar, MA Kharfan-Dabaja… - … and Cellular Therapy, 2022 - Elsevier
Chimeric antigen receptor T-cell therapy (CAR-T) is a major advance in managing
aggressive relapsed or refractory B-cell lymphomas; however, relapses are frequent and …