Antibiotic and antifungal resistance problems have been prevalent in recent decades. One
of the efforts to solve the problems is to develop new medicines with more potent …

Novel xanthine and imidazolone derivatives were synthesized based on oxazolone
derivatives 2a-c as a key intermediate. The corresponding xanthine 3-5 and imidazolone …

In this study, new benzimidazole-triazole derivatives were synthesized in two steps. First, 4-
benzaldehyde derivatives are synthesized by reacting 1, 2, 4-triazole ring and 4 …

Abstract The compound (E)-4-((4-hydroxy-3-methoxy-5-nitrobenzylidene) amino)-N-
(thiazole-2-yl) benzene sulfonamide (5NVTH) was synthesized and characterized by the …

A new series of 2, 4 disubstituted diarylpyrimidine derivatives has been designed,
synthesized and screened for their antibacterial activity. QSAR studies followed by …

Kinase enzymes play an important role in cellular proliferation, and inhibition of their activity
is a major goal of cancer therapy. Protein kinase inhibitors as benzimidazole derivatives can …

In this study, a series of phenyl, furyl and 1H‐1, 2, 4‐triazole substituted benzyl and alkyl
ethers were synthesized, characterized by all spectral analysis, and evaluated for their …

The multi-step synthesis, physico-chemical characterization, and biological activity of novel
valine-derived compounds, ie, N-acyl-α-amino acids, 1, 3-oxazol-5 (4 H)-ones, N-acyl-α …

A series of some novel 4H-benzoxazin-3-one derivative (1a-20a) was designed,
synthesized and evaluated as antifungal and anticancer agents. Benzoxazine compounds …

Background and Aims: Fungal infections continue to pose a serious threat to human well-
being due to the increasing cases of resistance against the existing antifungal drugs …