Prior qualitative literature reviews about the use of neuroleptics in dementia suggest that
they are “modestly effective” in treating agitation and that no single neuroleptic is better than …

Background: Neuroleptics are commonly used to treat behavioral disordersassociated with
dementia. However, their safety and efficacy have not been wellestablished in these …

A majority of demented patients experience agitation, psychotic symptoms, or other specific
behavioral problems at some time in the course of illness. Neuroleptics are the most widely …

The authors review the history of neuroleptic treatment in dementia. The initial review of 34
studies published since 1954 was limited to the 20 double‐blind and/or placebo‐controlled …

Among dementia patients in long-term care facilities, neuroleptics (NL) are frequently
prescribed for the treatment of agitation. Although good clinical practice and federal law …

Neuroleptic (antipsychotic) drugs are often used to treat psychiatric symptoms frequently
seen in dementia, but their use is controversial. We present a new meta-analysis to assess …

Background: Although few placebo-controlled neuroleptic discontinuation studies have
been conducted in people with dementia, such studies are essential to inform key clinical …

ContextNeuropsychiatric symptoms of dementia are common and associated with poor
outcomes for patients and caregivers. Although nonpharmacological interventions should be …

Pharmacotherapy of aggressive or agitated behaviors in the dementia patient has not been
studied extensively, despite the prevalence of this problem. Neuroleptics have the most …

Background There have been increasing concerns regarding the safety and efficacy of
neuroleptics in people with dementia, but there are very few long-term trials to inform clinical …