Stimulation of posterior thalamic nuclei induces photophobic behavior in mice

LP Sowers, M Wang, BJ Rea… - … : The Journal of …, 2020 - Wiley Online Library
Objective A hallmark of migraine is photophobia. In mice, photophobia‐like behavior is
induced by calcitonin gene‐related peptide (CGRP), a neuropeptide known to be a key …

Role of calcitonin gene-related peptide in light-aversive behavior: implications for migraine

A Recober, A Kuburas, Z Zhang… - Journal of …, 2009 - Soc Neuroscience
Migraine is a chronic neurological disorder characterized by recurrent episodes of severe
unilateral throbbing head pain and associated symptoms, such as photophobia. Our current …

Modulation of CGRP-induced light aversion in wild-type mice by a 5-HT1B/D agonist

EA Kaiser, A Kuburas, A Recober… - Journal of …, 2012 - Soc Neuroscience
The neuropeptide calcitonin gene-related peptide (CGRP) plays a critical role in the
pathophysiology of migraine. We have focused on the role of CGRP in photophobia, which …

Investigating migraine-like behavior using light aversion in mice

M Wang, BN Mason, LP Sowers, A Kuburas… - JoVE (Journal of …, 2021 - jove.com
Migraine is a complex neurological disorder characterized by headache and sensory
abnormalities, such as hypersensitivity to light, observed as photophobia. Whilst it is …

Induction of migraine-like photophobic behavior in mice by both peripheral and central CGRP mechanisms

BN Mason, EA Kaiser, A Kuburas… - Journal of …, 2017 - Soc Neuroscience
The neuropeptide calcitonin gene-related peptide (CGRP) is a key player in migraine.
Although migraine can be treated using CGRP antagonists that act peripherally, the relevant …

Induction of multiple photophobic behaviors in a transgenic mouse sensitized to CGRP

A Recober, EA Kaiser, A Kuburas, AF Russo - Neuropharmacology, 2010 - Elsevier
Migraine is a complex neurological disorder with a significant impact on patients and
society. Clinical and preclinical studies have established the neuropeptide calcitonin gene …

[HTML][HTML] CGRP administration into the cerebellum evokes light aversion, tactile hypersensitivity, and nociceptive squint in mice

M Wang, TL Duong, BJ Rea, JS Waite… - Frontiers in Pain …, 2022 - frontiersin.org
The neuropeptide calcitonin gene-related peptide (CGRP) is a major player in migraine
pathophysiology. Previous preclinical studies demonstrated that intracerebroventricular …

Photophobia in headache disorders: characteristics and potential mechanisms

Y Wang, S Wang, T Qiu, Z Xiao - Journal of Neurology, 2022 - Springer
Photophobia is present in multiple types of headache disorders. The coexistence of
photophobia and headache suggested the potential reciprocal interactions between visual …

Neurobiology of photophobia

R Burstein, R Noseda, AB Fulton - Journal of Neuro …, 2019 - journals.lww.com
Background: Photophobia is commonly associated with migraine, meningitis, concussion,
and a variety of ocular diseases. Advances in our ability to trace multiple brain pathways …

Advances in understanding the mechanisms of migraine-type photophobia

R Noseda, R Burstein - Current opinion in neurology, 2011 - journals.lww.com
Advances in understanding the mechanisms of migraine-type ph... : Current Opinion in
Neurology Advances in understanding the mechanisms of migraine-type photophobia : Current …