Dietary restriction (DR) is the most powerful intervention to enhance health and lifespan
across species. However, recent findings indicate that DR started in late life has limited …

Dietary restriction (DR) is the most consistent environmental manipulation to extend lifespan.
Originally thought to be caused by a reduction in caloric intake, recent evidence suggests …

Reducing food intake to induce undernutrition but not malnutrition extends the life spans of
multiple species, ranging from single-celled organisms to mammals. This increase in …

Dietary restriction (DR) and mutations in nutrient signaling pathways can extend healthy life
span in diverse organisms. Studying the interaction between these interventions should …

Dietary restriction (DR) extends life span across taxa. Despite considerable research,
universal mechanisms of DR have not been identified, limiting its translational potential …

Dietary restriction (DR), limiting nutrient intake from diet without causing malnutrition, delays
the aging process and extends lifespan in multiple organisms. The conserved life-extending …

Dietary restriction with adequate nutrition is the gold standard for delaying ageing and
extending healthspan and lifespan in diverse species, including rodents and non-human …

Dietary restriction (DR) under laboratory conditions generally extends life span and delays
ageing across species as diverse as yeast, nematode worms, flies and mice, and is …

Dietary restriction (DR) has long been viewed as the most robust nongenetic means to
extend lifespan and healthspan. Many aging-associated mechanisms are nutrient …

Dietary restriction (DR) extends the lifespan of a wide range of species, although the
universality of this effect has never been quantitatively examined. Here, we report the first …