Vasopressin: a first-line agent for septic shock?

JL Vincent, EH Post - Nature Reviews Nephrology, 2016 - nature.com
Noradrenaline is the currently recommended first-line vasopressor agent for patients with
refractory septic shock. Although vasopressin adjunct therapy might be beneficial, new data …

Effect of early vasopressin vs norepinephrine on kidney failure in patients with septic shock: the VANISH randomized clinical trial

AC Gordon, AJ Mason, N Thirunavukkarasu… - Jama, 2016 - jamanetwork.com
Importance Norepinephrine is currently recommended as the first-line vasopressor in septic
shock; however, early vasopressin use has been proposed as an alternative. Objective To …

The effects of vasopressin on acute kidney injury in septic shock

AC Gordon, JA Russell, KR Walley, J Singer… - Intensive care …, 2010 - Springer
Objective To compare the effects of vasopressin versus norepinephrine infusion on the
outcome of kidney injury in septic shock. Design and setting Post-hoc analysis of the multi …

Vasopressin in septic shock: an individual patient data meta-analysis of randomised controlled trials

M Nagendran, JA Russell, KR Walley, SJ Brett… - Intensive care …, 2019 - Springer
Purpose We performed an individual patient data meta-analysis to investigate the possible
benefits and harms of vasopressin therapy in adults with septic shock both overall and in pre …

Narrative review of controversies involving vasopressin use in septic shock and practical considerations

C Der-Nigoghossian, DA Hammond… - Annals of …, 2020 - journals.sagepub.com
Objective: To summarize literature evaluating vasopressin use, focusing on clinical
controversies regarding initiation, dosing, and discontinuation and interaction of vasopressin …

[HTML][HTML] Attempting to define and refine vasopressin use in septic shock: the VANISH trial

A Roy, RP Dellinger - Annals of translational medicine, 2016 - ncbi.nlm.nih.gov
Severe sepsis and septic shock are medical emergencies affecting almost 230,000
Americans every year with almost 40,000 deaths with an estimated cost of almost 25 billion …

[HTML][HTML] Nephroprotective strategies in septic shock: the VANISH trial

S Kwon, G Crowley, SH Haider, L Zhang… - Journal of Thoracic …, 2016 - ncbi.nlm.nih.gov
© Journal of Thoracic Disease. All rights reserved. J Thorac Dis 2016; 8 (11): E1508-E1510
jtd. amegroups. com vascular tone, has catecholamine-sparing effects, improve short-term …

[HTML][HTML] Vasopressin versus norepinephrine as the first-line vasopressor in septic shock: A systematic review and meta-analysis

YR Sedhai, DB Shrestha, P Budhathoki… - Journal of Clinical …, 2022 - ncbi.nlm.nih.gov
Methods: We selected studies in adults with septic shock that compared the outcomes of
patients treated with vasopressin versus norepinephrine. Cochrane ROB 2.0 and the …

Vasopressin versus norepinephrine infusion in patients with septic shock

JA Russell, KR Walley, J Singer… - … England Journal of …, 2008 - Mass Medical Soc
Background Vasopressin is commonly used as an adjunct to catecholamines to support
blood pressure in refractory septic shock, but its effect on mortality is unknown. We …

Vasopressin in septic shock: what we know and where to next?

PJ Young, A Delaney, B Venkatesh - Intensive Care Medicine, 2019 - Springer
Noradrenaline is the vasopressor administered most commonly to patients with distributive
shock [1]. However, in one study, 17.2% of patients with septic shock in United States …