The progesterone receptor (PgR), a member of the nuclear receptor family, is a well-known
oestrogen receptor (ER)-regulated gene that is expressed in over two-thirds of ER-positive …

Known risk factors for breast cancer include overexposure to exogenous or endogenous
hormones, namely, estrogen and progesterone. The effects of progesterone acts via two …

Background: Progesterone receptor (PR) expression assessment in early invasive breast
cancer remains controversial. This study sought to re-evaluate PR expression as a potential …

Hormone receptors represent the earliest biomarkers used in breast cancer not only as
prognosis markers but, in addition, to decide treatment. However, mostly estrogen receptors …

The progesterone receptor (PR) modulates estrogen receptors α (ERα) action in breast
cancer; it is an upregulated target gene of ER, and its expression is dependent on estrogen …

Estrogen receptor status in breast cancer is associated with response to hormonal therapy
and clinical outcome. The additional value of progesterone receptor (PR) has remained …

Progesterone and progesterone receptors (PR) have a storied albeit controversial history in
breast cancers. As endocrine therapies for breast cancer progressed through the twentieth …

The ovarian steroid hormones, estradiol and progesterone, and their nuclear receptors
(estrogen receptor [ER] and progesterone receptor [PR]), are involved in breast cancer …

Background The routine assessment of progesterone receptor (PR) expression in breast
cancer (BC) remains controversial. This study aimed to evaluate the role of PR expression in …

Background In breast cancer, progesterone receptor (PR) positivity or abundance is
positively associated with survival and treatment response. It was initially believed that PR …