Hormonal therapy of the brain-dead organ donor: experimental and clinical studies

D Novitzky, DKC Cooper, JD Rosendale… - …, 2006 - journals.lww.com
Abstract Experiments in Cape Town in the 1980s demonstrated that acute brain death is
followed by massive catecholamine release resulting in systemic hypertension, acute left …

Hormonal resuscitation yields more transplanted hearts, with improved early function1

JD Rosendale, HM Kauffman, MA McBride… - …, 2003 - journals.lww.com
Background. Brain death results in cardiovascular instability and poor organ perfusion in
many brain-dead donors. Hormonal resuscitation stabilizes certain brain-dead donors and is …

Hemodynamic and metabolic responses to hormonal therapy in brain-dead potential organ donors

D Novitzky, DKC Cooper, B Reichart - Transplantation, 1987 - journals.lww.com
HEMODYNAMIC AND METABOLIC RESPONSES TO HORMONAL THERAPY IN B... :
Transplantation HEMODYNAMIC AND METABOLIC RESPONSES TO HORMONAL …

Care of the potential organ donor

KE Wood, BN Becker, JG McCartney… - … England Journal of …, 2004 - Mass Medical Soc
Organ transplantation often depends on obtaining functioning organs from a donor who has
recently died. This review presents a structured approach to management of the care of the …

Aggressive pharmacologic donor management results in more transplanted organs1

JD Rosendale, HM Kauffman, MA McBride… - …, 2003 - journals.lww.com
Background. Brain death results in adverse pathophysiologic effects in many cadaveric
donors, resulting in cardiovascular instability and poor organ perfusion. Hormonal …

[PDF][PDF] A review of studies relating to thyroid hormone therapy in brain-dead organ donors

DK Cooper, D Novitzky, WN Wicomb, M Basker… - Front …, 2009 - article.imrpress.com
Introduction 3. Observations leading to the recognition of the deleterious effects of brain
death on donor organs 4. Management of the potential organ donor in 1981 5. Studies of …

A valid experimental brain death organ donor model.

HB Bittner, SW Kendall, KA Campbell… - The Journal of Heart …, 1995 - europepmc.org
Background This study was designed to establish a validated canine brain death model. Ten
consecutive dogs were studied to investigate the effects of brain death on hemodynamic …

Acute endocrine failure after brain death?

HJ Gramm, H Meinhold, U Bickel, J Zimmermann… - …, 1992 - journals.lww.com
After brain death, 32 potential organ donors were studied to determine serum and plasma
concentrations of hypothalamic-pituitary hormones, thyroid hormones, and cortisol over a …

The pathophysiological effects of brain death on potential donor organs, with particular reference to the heart.

DK Cooper, D Novitzky, WN Wicomb - Annals of the Royal College …, 1989 - ncbi.nlm.nih.gov
Major electrocardiographic, haemodynamic, and histopathological changes take place
during the development of brain death; myocardial and pulmonary injury may result …

Effects of hormonal supplements on the maintenance of cardiac function in potential donor patients after cerebral death

S Taniguchi, S Kitamura, K Kawachi… - European journal of …, 1992 - academic.oup.com
It is well-known that cardiac function in cerebrally dead patientsrapidly deteriorates, leaving
the organ unfit for donation. This studyinvestigated whether or not cardiac function in …