Genome-wide significant, replicated and functional risk variants for Alzheimer's disease
X Guo, W Qiu, R Garcia-Milian, X Lin, Y Zhang… - Journal of neural …, 2017 - Springer
Genome-wide association studies (GWASs) have reported numerous associations between
risk variants and Alzheimer's disease (AD). However, these associations do not necessarily …
risk variants and Alzheimer's disease (AD). However, these associations do not necessarily …
Polygenic risk and hazard scores for Alzheimer's disease prediction
Objective Genome‐wide association studies (GWAS) have identified over 30 susceptibility
loci associated with Alzheimer's disease (AD). Using AD GWAS data from the International …
loci associated with Alzheimer's disease (AD). Using AD GWAS data from the International …
An overview of genome-wide association studies in Alzheimer's disease
L Shen, J Jia - Neuroscience bulletin, 2016 - Springer
Genome-wide association studies (GWASs) have revealed a plethora of putative
susceptibility genes for Alzheimer's disease (AD). With the sole exception of the APOE gene …
susceptibility genes for Alzheimer's disease (AD). With the sole exception of the APOE gene …
Interpretation of 10 years of Alzheimer's disease genetic findings in the perspective of statistical heterogeneity
S Gao, T Wang, Z Han, Y Hu, P Zhu… - Briefings in …, 2024 - academic.oup.com
Common genetic variants and susceptibility loci associated with Alzheimer's disease (AD)
have been discovered through large-scale genome-wide association studies (GWAS) …
have been discovered through large-scale genome-wide association studies (GWAS) …
Genome-wide association studies for Alzheimer's disease: bigger is not always better
V Escott-Price, J Hardy - Brain Communications, 2022 - academic.oup.com
As the size of genome-wide association studies increase, the number of associated trait loci
identified inevitably increase. One welcomes this if it allows the better delineation of the …
identified inevitably increase. One welcomes this if it allows the better delineation of the …
[HTML][HTML] Associations of Alzheimer's disease risk variants with gene expression, amyloidosis, tauopathy, and neurodegeneration
MS Tan, YX Yang, W Xu, HF Wang, L Tan… - Alzheimer's Research & …, 2021 - Springer
Background Genome-wide association studies have identified more than 30 Alzheimer's
disease (AD) risk genes, although the detailed mechanism through which all these genes …
disease (AD) risk genes, although the detailed mechanism through which all these genes …
Genome-wide association studies in Alzheimer's disease
Genome-wide association studies (GWAS) have gained considerable momentum over the
last couple of years for the identification of novel complex disease genes. In the field of …
last couple of years for the identification of novel complex disease genes. In the field of …
[HTML][HTML] A transcriptome-wide association study of Alzheimer's disease using prediction models of relevant tissues identifies novel candidate susceptibility genes
Background Genome-wide association studies (GWAS) have identified over 56 susceptibility
loci associated with Alzheimer's disease (AD), but the genes responsible for these …
loci associated with Alzheimer's disease (AD), but the genes responsible for these …
Genome-wide association study identifies four novel loci associated with Alzheimer's endophenotypes and disease modifiers
More than 20 genetic loci have been associated with risk for Alzheimer's disease (AD), but
reported genome-wide significant loci do not account for all the estimated heritability and …
reported genome-wide significant loci do not account for all the estimated heritability and …
Genome-wide association analysis of age-at-onset in Alzheimer's disease
The risk of Alzheimer's disease (AD) is strongly determined by genetic factors and recent
genome-wide association studies (GWAS) have identified several genes for the disease risk …
genome-wide association studies (GWAS) have identified several genes for the disease risk …