[PDF][PDF] Association study of CYP3A5 genetic polymorphism with serum concentrations of carbamazepine in Chinese epilepsy patients
H Meng, J Ren, Y Lv, W Lin, Y Guo - Neurology Asia, 2011 - neurologyasia.org
Objective: To investigate the association between the CYP3A5 genetic polymorphism and
the serum concentrations of carbamazepine (CBZ), to provide guidance for individualized …
the serum concentrations of carbamazepine (CBZ), to provide guidance for individualized …
Effect of CYP3A5 genotypes on serum carbamazepine concentrations at steady-state in Vietnamese epileptic patients
TH Pham, HTM Huynh, HT Vo… - Research Journal of …, 2020 - indianjournals.com
Objective This study aims to investigate whether CYP3A5 polymorphisms affect steady-state
carbamazepine (CBZ) concentrations and therapeutic effects of CBZ monotherapy in …
carbamazepine (CBZ) concentrations and therapeutic effects of CBZ monotherapy in …
Effect of CYP3A5*3 genotype on serum carbamazepine concentrations at steady‐state in Korean epileptic patients
PW Park, YH Seo, JY Ahn, KA Kim… - Journal of clinical …, 2009 - Wiley Online Library
Abstract Background and Objective: Carbamazepine (CBZ) is metabolized mainly by the
CYP3A family of enzymes, which includes CYP3A4 and CYP3A5. Several studies have …
CYP3A family of enzymes, which includes CYP3A4 and CYP3A5. Several studies have …
Effects of CYP3A4/5 and ABCB1 genetic polymorphisms on carbamazepine metabolism and transport in Chinese patients with epilepsy treated with carbamazepine in …
P Wang, T Yin, HY Ma, DQ Liu, YH Sheng, C Wang… - Epilepsy research, 2015 - Elsevier
Objective To examine the effects of cytochrome P450 3A4 (CYP3A4), cytochrome P450 3A5
(CYP3A5) and ATP-binding cassette sub-family B member 1 (ABCB1) genetic …
(CYP3A5) and ATP-binding cassette sub-family B member 1 (ABCB1) genetic …
Pharmacogenetics of CYP3A5 on Carbamazepine pharmacokinetics in epileptic patients developing toxicity
M Al-Gahtany, G Karunakaran, M Munisamy - BMC Genomics, 2014 - Springer
Background The genetically polymorphic cytochrome P450 enzymes are involved in the
metabolism and elimination of a number of widely used drugs. CYP3A5 exhibits remarkable …
metabolism and elimination of a number of widely used drugs. CYP3A5 exhibits remarkable …
[HTML][HTML] Influence of cytochrome P450 3A5 (CYP3A5) genetic polymorphism on dose-adjusted plasma levels of carbamazepine in epileptic patients in South Indian …
M Ganesapandian, K Ramasamy… - Indian Journal of …, 2019 - journals.lww.com
AIM: The aim of the study was to compare the dose-adjusted plasma levels of
carbamazepine (CBZ) among expressers and nonexpressers of cytochrome P450 3A5 …
carbamazepine (CBZ) among expressers and nonexpressers of cytochrome P450 3A5 …
[HTML][HTML] Effects of CYP3A5 and UGT2B7 variants on steady-state carbamazepine concentrations in Chinese epileptic patients
Q Lu, YT Huang, Y Shu, P Xu, DX Xiang, Q Qu, J Qu - Medicine, 2018 - journals.lww.com
Carbamazepine (CBZ) is a widely used antiepileptic drug with large interindividual
variability in serum concentrations. Previous studies found that CYP3A5* 3 (rs776746) …
variability in serum concentrations. Previous studies found that CYP3A5* 3 (rs776746) …
Effects of major transporter and metabolizing enzyme gene polymorphisms on carbamazepine metabolism in Chinese patients with epilepsy
X Zhu, W Yun, X Sun, F Qiu, L Zhao, Y Guo - Pharmacogenomics, 2014 - Taylor & Francis
Aim: The present study aimed to evaluate the effects of SNPs of major transporter and
metabolizing enzyme genes on carbamazepine (CBZ) metabolism in Chinese patients with …
metabolizing enzyme genes on carbamazepine (CBZ) metabolism in Chinese patients with …
Effect of CYP3A5 genotypes on the pharmacokinetics of carbamazepine when used as monotherapy or co-administered with phenytoin, phenobarbital or valproic acid …
D Panomvana, T Traiyawong… - Journal of Pharmacy …, 2013 - journals.library.ualberta.ca
Purpose: To determine the effects of CYP3A5 polymorphisms on carbamazepine (CBZ)
pharmacokinetic parameters when CBZ is used either as monotherapy or co-administered …
pharmacokinetic parameters when CBZ is used either as monotherapy or co-administered …
CYP1A2 genotype affects carbamazepine pharmacokinetics in children with epilepsy
N Djordjevic, DD Milovanovic, M Radovanovic… - European journal of …, 2016 - Springer
Purpose The purpose of this study is to investigate the effect of two of the most important
functional CYP1A2 variations− 3860G> A and− 163C> A on carbamazepine …
functional CYP1A2 variations− 3860G> A and− 163C> A on carbamazepine …
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