Abstract Treatment of neuroepithelial cancers remains a daunting clinical challenge,
particularly due to an inability to address rampant invasion deep into eloquent regions of the …

Regulation of cell function by a non-thermal, physiological-level electromagnetic field has
potential for vascular tissue healing therapies and advancing hybrid bioelectronic …

Pulsed electric fields are increasingly used in medicine to transiently increase the cell
membrane permeability via electroporation to deliver therapeutic molecules into the cell …

Electric fields are known to produce biological effects. Depending on specific frequency,
they can stimulate healing, directly damage tissues, or produce anti-mitotic activity …

Glioblastoma is frequently associated with TP53 mutation, which is linked to a worse
prognosis and response to conventional treatments (chemoradiotherapy). Therefore …

Background/Aim: This proof-of-concept study evaluated the antitumor impact of a direct
electrical stimulation technique, termed intratumoral modulation therapy (IMT) on …

Glioblastoma multiforme (GBM) is the most common primary brain tumour in adults and
continues to portend poor survival, despite multimodal treatment using surgery and …

Alternating electric fields therapy, as delivered by the tumor treating fields device, is a new
modality of cancer treatment that has been approved by the US FDA for recurrent …

Background Glioblastoma multiforme (GBM) is the most aggressive primary brain
malignancy. Novel therapeutic modalities like tumor electric field therapy (TEFT) have …

Introduction: Tumor-treating fields (TTFs) are a specific local oncological treatment modality
in glioblastoma multiforme WHO° IV (GBM). Their mechanism of action is based on the effect …