Stomach regulates energy balance via acylated ghrelin and desacyl ghrelin

A Asakawa, A Inui, M Fujimiya, R Sakamaki… - Gut, 2005 - gut.bmj.com
Background/Aims: The gastric peptide ghrelin, an endogenous ligand for growth-hormone
secretagogue receptor, has two major molecular forms: acylated ghrelin and desacyl …

Ghrelin acts in the central nervous system to stimulate gastric acid secretion

Y Date, M Nakazato, N Murakami, M Kojima… - Biochemical and …, 2001 - Elsevier
Ghrelin is a novel acylated peptide that functions in the regulation of growth hormone
release and energy metabolism. It was isolated from rat stomach as an endogenous ligand …

Upregulation of ghrelin expression in the stomach upon fasting, insulin-induced hypoglycemia, and leptin administration

K Toshinai, MS Mondal, M Nakazato, Y Date… - Biochemical and …, 2001 - Elsevier
Ghrelin is a novel gut–brain peptide that binds to the growth hormone secretagogue
receptor (GHS-R), thereby functioning in the regulation of growth hormone (GH) release and …

[HTML][HTML] Effects of ghrelin in energy balance and body weight homeostasis

L Mihalache, A Gherasim, O Niţă, MC Ungureanu… - Hormones, 2016 - Springer
Ghrelin is a gut peptide composed of 28 amino acids mostly secreted in the gastric fundus
mucosa. It was isolated and described in 1999 by Kojima et al. and only three years later its …

Ghrelin, a gastrointestinal hormone, regulates energy balance and lipid metabolism

Y Lv, T Liang, G Wang, Z Li - Bioscience reports, 2018 - portlandpress.com
Ghrelin, an acylated peptide hormone of 28 amino acids, is an endogenous ligand of the
released growth hormone secretagogue receptor (GHSR). Ghrelin has been isolated from …

Energy homeostasis and gastric emptying in ghrelin knockout mice

B De Smet, I Depoortere, D Moechars… - … of Pharmacology and …, 2006 - ASPET
To elucidate the role of endogenous ghrelin in the regulation of energy homeostasis and
gastric emptying, ghrelin knockout mice (ghrelin-/-) were generated. Body weight, food …

Changes in ghrelin and ghrelin receptor expression according to feeding status

MS Kim, CY Yoon, KH Park, CS Shin, KS Park… - …, 2003 - journals.lww.com
Ghrelin, a newly identified gut hormone, has been implicated in the regulation of food intake
and energy homeostasis. This study was undertaken to investigate changes in expression …

Ghrelin: a novel player in the gut-brain regulation of growth hormone and energy balance

DH St-Pierre, L Wang, Y Taché - Physiology, 2003 - journals.physiology.org
Ghrelin is a newly discovered peptide hormone produced by the stomach that displays
potent growth hormone-releasing activity and a stimulatory effect on food intake and …

Antagonism of ghrelin receptor reduces food intake and body weight gain in mice

A Asakawa, A Inui, T Kaga, G Katsuura, M Fujimiya… - Gut, 2003 - gut.bmj.com
Background and aims: Ghrelin, an endogenous ligand for growth hormone secretagogue
receptor (GHS-R), is an appetite stimulatory signal from the stomach with structural …

[HTML][HTML] Ghrelin and the regulation of food intake and energy balance

H Hosoda, M Kojima… - Molecular …, 2002 - triggered.edina.clockss.org
Ghrelin, an endogenous ligand for the growth hormone secretagogue receptor, is
synthesized principally in the stomach and is released in response to acute and chronic …