The potential of cationic SiO2 nanoparticles was investigated for in vivo gene transfer in this
study. Cationic SiO2 nanoparticles with surface modification were generated using amino …

Silica-based nanoparticles are promising carriers for gene delivery applications. To gain
insights into the effect of particle size on gene transfection efficiency, amine-modified …

Diverse polycationic polymers have been used as nonviral transfection agents. Here we
report the ability of colloidal silica particles with covalently attached cationic surface …

In somatic gene therapy, new concepts for the transfer of DNA into specific cell nuclei are of
interest. Inorganic nanoparticles have an interesting potential as DNA carrier system due to …

Nanoparticles have an enormous potential for development in biomedical applications, such
as gene or drug delivery. We developed and characterized aminopropyltriethoxysilane …

Gene therapy has attracted much attention in modern society and provides a promising
approach for treating genetic disorders, diseases and cancers. Safe and effective vectors …

Silica nanoparticles are attractive candidates for the development of safe and efficient non-
viral gene carriers, owing to their controlled morphologies, potential of facile surface …

Poly-L-lysine-modified silica nanoparticles (PMS-NP) is a novel nonviral vector for gene
delivery, which can efficiently deliver plasmid DNA and antisense oligonucleotides into …

We have known for a while that silica is a promising candidate gene delivery vector. New in
vivo data from Dhruba Bharali and co-workers raise the hopes a notch for such approaches …

This article reports on the application of organically modified silica (ORMOSIL) nanoparticles
as a nonviral vector for efficient in vivo gene delivery. Highly monodispersed, stable …