Effect of low-dose oral contraceptives on androgenic markers and acne

IH Thorneycroft, FZ Stanczyk, KD Bradshaw… - Contraception, 1999 - Elsevier
Oral contraceptives (OC) suppress excess androgen production; however, different
progestins in combination with low-dose estrogens produce divergent effects on sex …

[PDF][PDF] Pharmacology of hormonal contraceptives and acne

K O'Connell, C Westhoff - Cutis, 2008 - cdn.mdedge.com
5α-reductase activity. The exact mechanism by which OCs reduce androgen production by
the adrenal glands is not known, though it has been demonstrated with radioimmune …

Efficacy of a low-dose oral contraceptive containing 20 μg of ethinyl estradiol and 100 μg of levonorgestrel for the treatment of moderate acne: A randomized, placebo …

J Leyden, A Shalita, M Hordinsky, L Swinyer… - Journal of the American …, 2002 - Elsevier
Background: Acne is a multifactorial disease in which androgens appear to play an
important role. A low-dose oral contraceptive containing 20 μg of ethinyl estradiol and 100 …

Oral contraceptives as anti-androgenic treatment of acne

A Lemay, Y Poulin - Journal of Obstetrics and Gynaecology Canada, 2002 - Elsevier
Although acne is seldom associated with high serum levels of androgens, it has been shown
that female acne patients have definite increases in ovarian and adrenal androgen levels …

Effects of seven low-dose combined oral contraceptives on sex hormone binding globulin, corticosteroid binding globulin, total and free testosterone

N Van der Vange, MA Blankenstein, HJ Kloosterboer… - Contraception, 1990 - Elsevier
The effect of seven low-dose oral contraceptive preparations on sex hormone binding
globulin (SHBG), corticol binding globulin (CBG), total and absolute free testosterone were …

The effect of combined oral contraception on testosterone levels in healthy women: a systematic review and meta-analysis

Y Zimmerman, MJC Eijkemans… - Human reproduction …, 2014 - academic.oup.com
BACKGROUND Combined oral contraceptives (COCs) reduce levels of androgen,
especially testosterone (T), by inhibiting ovarian and adrenal androgen synthesis and by …

Attenuation of mild hyperandrogenic activity in postpubertal acne by a triphasic oral contraceptive containing low doses of ethynyl estradiol and d, l-norgestrel

A LEMAY, SD DEWAILLY, R GRENIER… - The Journal of Clinical …, 1990 - academic.oup.com
The effect of a low dose triphasic oral contraceptive (OC) was evaluated during a 6-month
treatment period in 41 patients (mean age, 25.4±0.7 yr) who had grade I-IV postpubertal …

A randomized controlled trial of second-versus third-generation oral contraceptives in the treatment of acne vulgaris

MP Rosen, DM Breitkopf, M Nagamani - American journal of obstetrics and …, 2003 - Elsevier
Objective: This study was undertaken to compare the clinical efficacy of second-versus third-
generation oral contraceptives in the treatment of acne. Study Design: Thirty-four women …

Noncontraceptive benefits of oral contraceptive use: an evidence-based approach.

JK Williams - International journal of fertility and women's medicine, 2000 - europepmc.org
Numerous noncontraceptive benefits of oral contraceptive (OC) use have been identified.
These include a reduction in ovarian and endometrial cancers, functional ovarian cysts …

Effect of oral versus transdermal steroidal contraceptives on androgenic markers

T White, JK Jain, FZ Stanczyk - American journal of obstetrics and …, 2005 - Elsevier
OBJECTIVE: The purpose of this study was to compare biochemical androgen profiles in
women treated with the contraceptive patch versus an oral contraceptive (OC). STUDY …