DNA methylation and high-density lipoprotein functionality—brief report: The REGICOR study (Registre Gironi del Cor)
S Sayols-Baixeras, A Hernáez, I Subirana… - … , and vascular biology, 2017 - Am Heart Assoc
Objective—The function of high-density lipoproteins (HDLs) may better reflect their
atheroprotective role, compared with HDL-cholesterol levels. The association between DNA …
atheroprotective role, compared with HDL-cholesterol levels. The association between DNA …
DNA methylation variations at CETP and LPL gene promoter loci: new molecular biomarkers associated with blood lipid profile variability
SP Guay, D Brisson, B Lamarche, P Marceau, MC Vohl… - Atherosclerosis, 2013 - Elsevier
BACKGROUND: Recent findings suggest that DNA methylation, a well-known epigenetic
mechanism, is involved in high-density lipoprotein cholesterol (HDL-C) metabolism and …
mechanism, is involved in high-density lipoprotein cholesterol (HDL-C) metabolism and …
A study in familial hypercholesterolemia suggests reduced methylomic plasticity in men with coronary artery disease
Aim: To assess whether DNA methylation is associated with coronary artery disease (CAD).
Materials & methods: An epigenome-wide analysis has been performed on leucocytes from …
Materials & methods: An epigenome-wide analysis has been performed on leucocytes from …
Epigenome-wide analysis in familial hypercholesterolemia identified new loci associated with high-density lipoprotein cholesterol concentration
SP Guay, G Voisin, D Brisson, J Munger… - …, 2012 - Taylor & Francis
Aim: This study aims to assess whether epigenetic changes may account for high-density
lipoprotein cholesterol (HDL-C) level variability in familial hypercholesterolemia (FH), a …
lipoprotein cholesterol (HDL-C) level variability in familial hypercholesterolemia (FH), a …
The role of DNA methylation in dyslipidaemia: a systematic review
KVE Braun, T Voortman, K Dhana, J Troup… - Progress in Lipid …, 2016 - Elsevier
Epigenetic mechanisms, including DNA methylation and histone modifications, might be
involved in the regulation of blood lipid concentration variability and may thereby affect …
involved in the regulation of blood lipid concentration variability and may thereby affect …
DNA methylation profiling identifies a high effect genetic variant for lipoprotein (a) levels
Changes in whole blood DNA methylation levels at several CpG sites have been associated
with circulating blood lipids, specifically high-density lipoprotein and triglycerides. This study …
with circulating blood lipids, specifically high-density lipoprotein and triglycerides. This study …
DNA methylation of lipid-related genes affects blood lipid levels
L Pfeiffer, S Wahl, LC Pilling, E Reischl… - Circulation …, 2015 - Am Heart Assoc
Background—Epigenetic mechanisms might be involved in the regulation of interindividual
lipid level variability and thus may contribute to the cardiovascular risk profile. The aim of this …
lipid level variability and thus may contribute to the cardiovascular risk profile. The aim of this …
Atherosclerosis: cell biology and lipoproteins–panoramic views of DNA methylation landscapes of atherosclerosis
During the last 2 years, the cardiovascular disease (CVD) field has increasingly embraced
epigenomics technologies. This ménage is a young one in comparison with cancer studies …
epigenomics technologies. This ménage is a young one in comparison with cancer studies …
Epigenome-wide association study (EWAS) on lipids: the Rotterdam Study
Background DNA methylation is a key epigenetic mechanism that is suggested to be
associated with blood lipid levels. We aimed to identify CpG sites at which DNA methylation …
associated with blood lipid levels. We aimed to identify CpG sites at which DNA methylation …
Lipid phenotypes and DNA methylation: a review of the literature
Abstract Purpose of Review Epigenetic modifications via DNA methylation have previously
been linked to blood lipid levels, dyslipidemias, and atherosclerosis. The purpose of this …
been linked to blood lipid levels, dyslipidemias, and atherosclerosis. The purpose of this …