Fragile X syndrome (FXS) is a monogenic mental retardation syndrome that frequently
includes autism. The Fmr1‐knockout (Fmr1‐KO) mouse, like FXS‐affected individuals, lacks …

Fragile X syndrome (FXS), resulting solely from the loss of function of the human fragile X
mental retardation 1 (hFMR1) gene, is the most common heritable cause of mental …

Fragile X syndrome (FXS) is the most common form of inherited intellectual disability and is
caused by a loss of function of the fragile X mental retardation (fmr1) gene. Animal fmr1 …

Fragile X syndrome (FXS), a single gene disorder with an expanded CGG allele on the X
chromosome, is the most common form of inherited cognitive impairment. The cognitive …

Trace fear memory requires the activity of the anterior cingulate cortex (ACC) and is
sensitive to attention-distracting stimuli. Fragile X syndrome is the most common form of …

Fragile X syndrome (FXS) is the most common inherited cause of mental retardation. It is
also one of the most common identifiable causes of Autism Spectrum Disorder (ASD) …

Background Fragile X syndrome is caused by loss of function of the fragile X mental
retardation 1 (FMR1) gene and shares multiple phenotypes with autism. We have previously …

The mental retardation, autistic features, and behavioral abnormalities characteristic of the
Fragile X mental retardation syndrome result from the loss of function of the RNA–binding …

The fragile X mental retardation protein (FMRP) plays an important role in normal brain
development. Absence of FMRP results in abnormal neuronal morphologies in a selected …

The fragile X mental retardation 1 gene (FMR 1)‐related disorder fragile X syndrome (FXS)
is the most common heritable form of cognitive impairment and the second most common …