Non-vitamin K antagonist oral anticoagulants for stroke prevention in atrial fibrillation: safety issues in the elderly

T Ajam, TL Cumpian, BL Tilkens… - Expert Review of …, 2020 - Taylor & Francis
Introduction Non-vitamin K antagonist oral anticoagulants (NOACs) are increasingly used for
stroke prevention in patients with atrial fibrillation (AF). Since NOACs are predominantly …

Non-vitamin K antagonist oral anticoagulants in elderly patients with atrial fibrillation: A systematic review with meta-analysis and trial sequential analysis

D Caldeira, A Nunes-Ferreira, R Rodrigues… - Archives of Gerontology …, 2019 - Elsevier
Background: Elderly population is known to be associated with polymedication,
comorbidities and altered drug pharmacokinetics. However, the most adequate oral …

[HTML][HTML] Effectiveness and safety of oral anticoagulants in older patients with atrial fibrillation: a systematic review and meta-analysis

M Grymonprez, S Steurbaut, TL De Backer… - Frontiers in …, 2020 - frontiersin.org
Background and Objective Atrial fibrillation (AF), the most common cardiac arrhythmia,
typically increases with age. Oral anticoagulants (OACs) are the cornerstone of treatment to …

Optimal anticoagulation in elderly patients with atrial fibrillation: Which drug at which dose?

JN Liao, YH Chan, L Kuo, CT Tsai… - Polish Heart Journal …, 2022 - journals.viamedica.pl
Aging is an important risk factor for adverse events in elderly patients with atrial fibrillation
(AF) and complicates the management of anticoagulation. Underuse of oral anticoagulants …

Safety and efficacy of non-vitamin K antagonist oral anticoagulants in elderly patients with atrial fibrillation: systematic review and meta-analysis of 22 studies and 440 …

A Silverio, M Di Maio, C Prota… - European Heart …, 2021 - academic.oup.com
Aims The aim of the present meta-analysis was to evaluate the efficacy and safety of non-
vitamin K oral antagonists (NOACs) vs. vitamin K antagonists (VKAs) in elderly patients with …

[HTML][HTML] Unmet clinical needs in elderly patients receiving direct Oral anticoagulants for stroke prevention in non-valvular atrial fibrillation

G Botto, P Ameri, M Cappellari, F Dentali, N Ferri… - Advances in …, 2021 - Springer
Vitamin K antagonists have been used for many years as the treatment of choice for long-
term oral anticoagulation in patients with non-valvular atrial fibrillation. Unfortunately, the …

Non–Vitamin K Antagonist Oral Anticoagulants in Elderly (≥ 85 years) Patients With Newly Diagnosed Atrial Fibrillation: Changing Clinical Practice and Outcomes for …

WH Cheng, CE Chiang, YJ Lin, SL Chang, LW Lo… - Mayo Clinic …, 2021 - Elsevier
Objective To investigate the influences of non–vitamin K antagonist oral anticoagulants
(NOACs) on rates of initiations of oral anticoagulants (OACs) and outcomes among elderly …

Novel oral anticoagulants for stroke prevention in atrial fibrillation: a focus on the older patient

SW Yates - International Journal of General Medicine, 2013 - Taylor & Francis
Atrial fibrillation (AF) is a common arrhythmia that is associated with an increased risk of
stroke, particularly in the elderly. Traditionally, a vitamin K antagonist such as warfarin is …

[HTML][HTML] Effectiveness and safety of direct oral anticoagulants versus vitamin K antagonists for people aged 75 years and over with atrial fibrillation: a systematic review …

A Mitchell, MC Watson, T Welsh… - Journal of clinical medicine, 2019 - mdpi.com
Older people, are underrepresented in randomised controlled trials of direct oral
anticoagulants (DOACs) for stroke prevention in atrial fibrillation (AF). The aim of this study …

The safety of NOAC s in atrial fibrillation patient subgroups: A narrative review

GYH Lip - International Journal of Clinical Practice, 2019 - Wiley Online Library
Aim Four non‐vitamin K oral anticoagulants (NOAC s) have been evaluated in clinical trials
for the prevention of stroke in patients with atrial fibrillation (AF). Although each of the NOAC …