Amiodarone (AD) is gaining support as a first-line antiarrhythmic drug despite its potentially
fatal pulmonary toxicity involving inflammation and fibrosis. The goals of this study were to …

Amiodarone (AD) is a highly efficient antiarrhythmic drug with potentially serious side effects.
Severe pulmonary toxicity is reported in patients receiving AD even at low doses and may …

Amiodarone (AD) is gaining support as a first-line antiarrhythmic drug despite its potentially
fatal pulmonary toxicity involving inflammation and fibrosis. We previously reported a model …

Toinvestigate the hypotheses that amiodarone-induced pulmonary inflammation may be
related to direct drug toxicity, groups of 10or more Wistar rats were fed amiodarone by …

Amiodarone (AD) has been shown to produce a transient pulmonary fibrosis in hamsters
after intratracheal (it) instillation. The goal of this study was to examine bronchoalveolar …

Amiodarone (AM), a drug used in the treatment of cardiac dysrrhythmias, can produce
severe pulmonary adverse effects, including fibrosis. Although the pathogenesis of AM …

The use of the antiarrythmic drug amiodarone (AD) has been limited by the propensity of the
drug to cause severe lung damage. AD has been shown to produce a transient pulmonary …

The potent and efficacious anti-dysrhythmic agent amiodarone (AM) can cause potentially
life-threatening lung damage (amiodarone-induced pulmonary toxicity; AIPT), which is …

Amiodarone is an antiarrhythmic drug with numerous side effects, the most serious being the
development of pulmonary toxicity. We have previously reported that a single intratra cheal …

Background: The clinical usefulness of amiodarone for the treatment of cardiac arrhythmias
is limited by multiorgan toxicity, especially pulmonary and hepatic. There are conflicting …