Surface conjugation of curcumin with self-assembled lysozyme nanoparticle enhanced its bioavailability and therapeutic efficacy in multiple cancer cells

P Somu, S Paul - Journal of Molecular Liquids, 2021 - Elsevier
Here, we prepared nano self-assembly of lysozyme via a directed optimized desolvation
process and conjugated it with an anticancer natural polyphenol, curcumin (Cur) onto the …

Bio-conjugation of curcumin with self-assembled casein nanostructure via surface loading enhances its bioactivity: an efficient therapeutic system

P Somu, S Paul - Applied Surface Science, 2018 - Elsevier
In this study, self-assembled nanostructure of casein (NS CS) of spherical shape was
prepared using an optimized desolvation method with a mean size of 45 nm. Curcumin …

Supramolecular nanoassembly of lysozyme and α-lactalbumin (apo α-LA) exhibits selective cytotoxicity and enhanced bioavailability of curcumin to cancer cells

P Somu, S Paul - Colloids and Surfaces B: Biointerfaces, 2019 - Elsevier
Hybrid supramolecular spherical nanoassembly of hen egg white lysozyme and bovine apo
α lactalbumin (SN LYZ-BLA) was prepared with a mean size of˜ 55.2 nm using an optimized …

Bioinspired synthesis of protein/polysaccharide-decorated folate as a nanocarrier of curcumin to potentiate cancer therapy

NS Elbialy, SF Aboushoushah, N Mohamed - International Journal of …, 2022 - Elsevier
Curcumin is a promising anticancer agent, but its clinical utilization has been hindered by its
low solubility and bioaccessibility. To overcome these obstacles, we developed a natural …

Amphiphilic curcumin conjugate-forming nanoparticles as anticancer prodrug and drug carriers: in vitro and in vivo effects

H Tang, CJ Murphy, B Zhang, Y Shen, M Sui… - …, 2010 - Future Medicine
Curcumin has been shown to have high cytotoxicity towards various cancer cell lines, but its
water insolubility and instability make its bioavailability exceedingly low and, thus, it is …

Effect of chemical linkers of curcumin conjugated hyaluronic acid on nanoparticle properties and in vitro performances in various cancer cells

P Thummarati, J Suksiriworapong, K Sakchaisri… - Journal of Drug Delivery …, 2021 - Elsevier
Chemical linkers play an important role in determining the physicochemical properties,
stability and cytotoxic activities of nanoparticles for cancer treatment. Herein, curcumin …

Redox responsive xylan-SS-curcumin prodrug nanoparticles for dual drug delivery in cancer therapy

B Kumar, R Priyadarshi, F Deeba… - Materials Science and …, 2020 - Elsevier
Chemotherapeutic agents with different anticancer mechanisms could enhance therapeutic
effect in cancer therapy by their combined application. In this study, redox-sensitive prodrug …

Synergistic chemotherapeutic activity of curcumin bearing methoxypolyethylene glycol-g-linoleic acid based micelles on breast cancer cells

S Guzzarlamudi, PK Singh, VK Pawar… - … of nanoscience and …, 2016 - ingentaconnect.com
Although curcumin (Cur), has been poised to be an anticancer boon for quite some, its
progress from bench to bed has been strained due to various pharmaceutical hurdles …

pH-responsive prodrug nanoparticles based on xylan-curcumin conjugate for the efficient delivery of curcumin in cancer therapy

SU Kumar, V Kumar, R Priyadarshi, P Gopinath… - Carbohydrate …, 2018 - Elsevier
In the present study, novel pH-responsive prodrug nanoparticles based on xylan-curcumin
(xyl-cur) conjugate were developed to enhance the therapeutic efficacy of curcumin in …

Doxorubicin‐anchored curcumin nanoparticles for multimode cancer treatment against human liver carcinoma cells

V Rajiu, P Balaji, TS Sheena… - Particle & particle …, 2015 - Wiley Online Library
Curcumin (Curcuma longa L), a yellow‐colored Indian spice, receives immense attention for
the prevention and treatment of various cancers. Despite the superlative therapeutic efficacy …