More than 300 years ago Antoni van Leeuwenhoek described crystals of biological
materials derived from human semen. A further 250 years were to pass before the structure …

The history of polyamines dates back to the fifteenth century when spermine was discovered
by Antonie van Leeuwenhoek [born in Delft, Holland (1632–1723)], but it took several …

The polyamines, spermidine and spermine, were first discovered in 1678 by Antonie van
Leeuwenhoek. In the early part of the 20th century their structure was determined (Figure 1) …

In 1678 Antonie van Leeuwenhoek identified crystalline substances in human semen. The
structure of these crystals, named “spermine”, was not elucidated by Rosenheim until 250 …

Polyamines have a long history in biochemistry and physiology, dating back to 1678 when
Leeuwenhoek first reported crystals that were composed of spermine phosphate in seminal …

Although receiving little attention in biochemical and physiological textbooks, the
polyamines have a long history and have accumulated a considerable literature (for reviews …

PerspectivesinBiologyandMedicine· Spring1979\421 metabolism of polyamines have been
uncovered in animals, plants, and microorganisms. Various polyamine biosynthetic …

This chapter provides an overview of the polyamine field and introduces the 32 other
chapters that make up this volume. These chapters provide a wide range of methods …

(20). This procedure involves oxidizing the polyamines by serum amine ox idase and then
adding N-methyl-2-benzothiazolone hydrazone hydrochloride (NBTH). This method, which …

The naturally occurring polyamines are found in all living cells, where they fulfil a number of
critical functions in relation to cell growth. The quest to identify these functions has been the …