[HTML][HTML] Mechanisms of Cryptococcus neoformans-Mediated Host Damage

A Casadevall, C Coelho, A Alanio - Frontiers in immunology, 2018 - frontiersin.org
Cryptococcus neoformans is not usually considered a cytotoxic fungal pathogen but there is
considerable evidence that this microbe can damage host cells and tissues. In this essay …

The Intracellular Life of Cryptococcus neoformans

C Coelho, AL Bocca… - Annual Review of …, 2014 - annualreviews.org
Cryptococcus neoformans is a fungal pathogen with worldwide distribution. Serological
studies of human populations show a high prevalence of human infection, which rarely …

Cryptococcus neoformans–induced macrophage lysosome damage crucially contributes to fungal virulence

MJ Davis, AJ Eastman, Y Qiu, B Gregorka… - The Journal of …, 2015 - journals.aai.org
Upon ingestion by macrophages, Cryptococcus neoformans can survive and replicate
intracellularly unless the macrophages become classically activated. The mechanism …

[HTML][HTML] Dangerous Liaisons: Interactions of Cryptococcus neoformans with Host Phagocytes

EA Gaylord, HL Choy, TL Doering - Pathogens, 2020 - mdpi.com
Cryptococcus neoformans is an opportunistic fungal pathogen and a leading cause of death
in immunocompromised individuals. The interactions of this yeast with host phagocytes are …

[HTML][HTML] A Sensitive High-Throughput Assay for Evaluating Host-Pathogen Interactions in Cryptococcus neoformans Infection

D Srikanta, M Yang, M Williams, TL Doering - PLoS One, 2011 - journals.plos.org
Background Cryptococcus neoformans causes serious disease in immunocompromised
individuals, leading to over 600,000 deaths per year worldwide. Part of this impact is due to …

[HTML][HTML] Cryptococcus and Phagocytes: Complex Interactions that Influence Disease Outcome

CM Leopold Wager, CR Hole, KL Wozniak… - Frontiers in …, 2016 - frontiersin.org
Cryptococcus neoformans and C. gattii are fungal pathogens that cause life-threatening
disease. These fungi commonly enter their host via inhalation into the lungs where they …

Catch me if you can: phagocytosis and killing avoidance by Cryptococcus neoformans

R Garcia-Rodas, O Zaragoza - FEMS Immunology & Medical …, 2012 - academic.oup.com
After inhalation of infectious particles, Cryptococcus neoformans resides in the alveolar
spaces, where it can survive and replicate in the extracellular environment. This yeast has …

Cryptococcus neoformans and Cryptococcus gattii clinical isolates from Thailand display diverse phenotypic interactions with macrophages

A Hansakon, P Mutthakalin, P Ngamskulrungroj… - Virulence, 2019 - Taylor & Francis
Cryptococcus-macrophage interaction is crucial in the development of cryptococcocal
diseases. C. neoformans and C. gattii are major pathogenic species that occupy different …

[HTML][HTML] Cryptococcus escapes host immunity: What do we know?

C Yang, Y Huang, Y Zhou, X Zang, H Deng… - Frontiers in Cellular …, 2022 - frontiersin.org
Cryptococcus is an invasive fungus that seriously endangers human life and health, with a
complex and well-established immune-escaping mechanism that interferes with the function …

The tools for virulence of Cryptococcus neoformans

C Coelho, AL Bocca, A Casadevall - Advances in applied microbiology, 2014 - Elsevier
Cryptococcus neoformans is a fungal pathogen that causes almost half a million deaths
each year. It is believed that most humans are infected with C. neoformans, possibly in a …