Autophagy induction regulates aquaporin 3‐mediated skin fibroblast ageing

H Xie, L Zhou, F Liu, J Long, S Yan… - British Journal of …, 2022 - academic.oup.com
Background Long‐and short‐term ultraviolet (UV) exposure have distinct biological effects
on human fibroblasts. Objectives To elucidate the underlying mechanisms of the biological …

Protective role of AQP3 in UVA-induced NHSFs apoptosis via Bcl2 up-regulation

H Xie, F Liu, L Liu, J Dan, Y Luo, Y Yi, X Chen… - Archives of …, 2013 - Springer
Abstract Aquaporin-3 (AQP3), a water/glycerol-transporting protein that facilitates water,
urea, and glycerol transport, can inhibit arsenite-induced apoptosis by up-regulating Bcl-2 …

Trans-Zeatin attenuates ultraviolet induced down-regulation of aquaporin-3 in cultured human skin keratinocytes

C Ji, Y Yang, B Yang, J Xia, W Sun… - International …, 2010 - spandidos-publications.com
Solar ultraviolet (UV) irradiation is one of the most significant extrinsic factors contributing to
skin photoaging. One major characteristic of photoaging induced by UV is water loss of the …

Autophagy: multiple mechanisms to protect skin from ultraviolet radiation‐driven photoaging

M Wang, P Charareh, X Lei… - Oxidative Medicine and …, 2019 - Wiley Online Library
Autophagy is an essential cellular process that maintains balanced cell life. Restriction in
autophagy may induce degenerative changes in humans. Natural or pathological aging of …

Autophagy in UV damage response

A Sample, YY He - Photochemistry and photobiology, 2017 - Wiley Online Library
UV radiation exposure from sunlight and artificial tanning beds is the major risk factor for the
development of skin cancer and skin photoaging. UV‐induced skin damage can trigger a …

[HTML][HTML] Ultraviolet B radiation down-regulates ULK1 and ATG7 expression and impairs the autophagy response in human keratinocytes

X Chen, L Li, S Xu, W Bu, K Chen, M Li, H Gu - Journal of Photochemistry …, 2018 - Elsevier
Autophagy is a self-digestive pathway that helps to maintain cellular homeostasis, and many
autophagy-related gene (ATG) s involved the regulation of the autophagy process …

Autophagy plays an essential role in ultraviolet radiation-driven skin photoaging

J Ma, Y Teng, Y Huang, X Tao, Y Fan - Frontiers in Pharmacology, 2022 - frontiersin.org
Photoaging is characterized by a chronic inflammatory response to UV light. One of the most
prominent features of cutaneous photoaging is wrinkling, which is due primarily to a loss of …

AQP5 regulates the proliferation and differentiation of epidermal stem cells in skin aging

J Zhou, Y Dong, J Liu, J Ren, J Wu… - Brazilian Journal of …, 2020 - SciELO Brasil
The epidermis, the outermost layer of the skin, is the first barrier that comes into contact with
the external environment. It plays an important role in resisting the invasion of harmful …

Synergistic interplay of UV radiation and urban particulate matter induces impairment of autophagy and alters cellular fate in senescence‐prone human dermal …

L Guerrero‐Navarro, P Jansen‐Dürr, M Cavinato - Aging Cell, 2024 - Wiley Online Library
Skin aging is a complex process influenced by intrinsic factors and environmental stressors,
including ultraviolet (UV) radiation and air pollution, among others. In this study, we …

UVB-induced senescence of human dermal fibroblasts involves impairment of proteasome and enhanced autophagic activity

M Cavinato, R Koziel, N Romani… - … Series A: Biomedical …, 2017 - academic.oup.com
In the current study, we have extended previous findings aiming at a better understanding of
molecular mechanisms underlying UVB-induced senescence of diploid human dermal …