Advances in the treatment of neurodegenerative disorders employing nanotechnology

G Modi, V Pillay, YE Choonara - … of the New York Academy of …, 2010 - Wiley Online Library
Due to limitations posed by the restrictive blood–brain barrier, conventional drug delivery
systems do not provide adequate cyto‐architecture restoration and connection patterns that …

Nanotechnological applications for the treatment of neurodegenerative disorders

G Modi, V Pillay, YE Choonara, VMK Ndesendo… - Progress in …, 2009 - Elsevier
Nanotechnology employs engineered materials or devices that interact with biological
systems at a molecular level and could revolutionize the treatment of neurodegenerative …

[HTML][HTML] Nano biomaterials based strategies for enhanced brain targeting in the treatment of neurodegenerative diseases: an up-to-date perspective

DE Nayab, F Din, H Ali, WA Kausar, S Urooj… - Journal of …, 2023 - Springer
Neurons and their connecting axons gradually degenerate in neurodegenerative diseases
(NDs), leading to dysfunctionality of the neuronal cells and eventually their death. Drug …

[HTML][HTML] A review of the common neurodegenerative disorders: current therapeutic approaches and the potential role of nanotherapeutics

RNL Lamptey, B Chaulagain, R Trivedi… - International journal of …, 2022 - mdpi.com
Neurodegenerative disorders are primarily characterized by neuron loss. The most common
neurodegenerative disorders include Alzheimer's and Parkinson's disease. Although there …

Alzheimer's disease and Parkinson's disease: a review of current treatment adopting a nanotechnology approach

A Trompetero, A Gordillo, MC del Pilar… - Current …, 2018 - ingentaconnect.com
Neurodegenerative disorders (NDDs) are characterized by the progressive loss of structure
or neuron function, often associated with neuronal death. Treatments for neurodegenerative …

[HTML][HTML] Nanomedicine in the management of Alzheimer's disease: State-of-the-art

SN Mir Najib Ullah, O Afzal, ASA Altamimi, H Ather… - Biomedicines, 2023 - mdpi.com
Alzheimer's disease (AD) is a deadly, progressive, and irreversible brain condition that
impairs cognitive abilities. Globally, it affects 32.6 million individuals, and if no viable …

[HTML][HTML] Nanoparticle-guided brain drug delivery: Expanding the therapeutic approach to neurodegenerative diseases

C Riccardi, F Napolitano, D Montesarchio, S Sampaolo… - Pharmaceutics, 2021 - mdpi.com
Neurodegenerative diseases (NDs) represent a heterogeneous group of aging-related
disorders featured by progressive impairment of motor and/or cognitive functions, often …

Neurodegenerative disorders and nanoformulated drug development

A Nowacek, LM Kosloski, HE Gendelman - Nanomedicine, 2009 - Taylor & Francis
Degenerative and inflammatory diseases of the CNS include, but are not limited to,
Alzheimer's and Parkinson's disease, amyotrophic lateral sclerosis, stroke, multiple sclerosis …

[HTML][HTML] Nanomedicine: A Promising way to manage Alzheimer's disease

NH Khan, M Mir, EE Ngowi, U Zafar… - … in Bioengineering and …, 2021 - frontiersin.org
Alzheimer's disease (AD) is a devastating disease of the aging population characterized by
the progressive and slow brain decay due to the formation of extracellular plaques in the …

[HTML][HTML] Recent advances in the treatment of Alzheimer's disease using nanoparticle-based drug delivery systems

P Poudel, S Park - Pharmaceutics, 2022 - mdpi.com
Alzheimer's disease (AD) is an irreversible and progressive neurodegenerative disorder.
Most existing treatments only provide symptomatic solutions. Here, we introduce currently …