[HTML][HTML] Mesenchymal stem cell exosomes as a new strategy for the treatment of diabetes complications

J Xiong, H Hu, R Guo, H Wang, H Jiang - Frontiers in Endocrinology, 2021 - frontiersin.org
Diabetes mellitus (DM) is a metabolic disease, now prevalent worldwide, which is
characterized by a relative or absolute lack of insulin secretion leading to chronically …

[HTML][HTML] The roles of mesenchymal stem cell-derived exosomes in diabetes mellitus and its related complications

M Yang, J Chen, L Chen - Frontiers in Endocrinology, 2022 - frontiersin.org
Diabetes mellitus is a type of metabolic disease characterized by hyperglycemia, primarily
caused by defects in insulin secretion, insulin action, or both. Long-term chronic …

Human mesenchymal stem cell derived exosomes alleviate type 2 diabetes mellitus by reversing peripheral insulin resistance and relieving β-cell destruction

Y Sun, H Shi, S Yin, C Ji, X Zhang, B Zhang, P Wu… - ACS …, 2018 - ACS Publications
Exosomes are nanosized extracellular vesicles (EVs) that show great promise in tissue
regeneration and injury repair as mesenchymal stem cell (MSC). MSC has been shown to …

[HTML][HTML] Mesenchymal stem cell-derived exosomes: The dawn of diabetic wound healing

J Wu, LH Chen, SY Sun, Y Li, XW Ran - World Journal of Diabetes, 2022 - ncbi.nlm.nih.gov
Chronic wound healing has long been an unmet medical need in the field of wound repair,
with diabetes being one of the major etiologies. Diabetic chronic wounds (DCWs), especially …

[HTML][HTML] Exosomes derived from atorvastatin-pretreated MSC accelerate diabetic wound repair by enhancing angiogenesis via AKT/eNOS pathway

M Yu, W Liu, J Li, J Lu, H Lu, W Jia, F Liu - Stem cell research & therapy, 2020 - Springer
Background Mesenchymal stem cell (MSC)-derived exosomes emerge as promising
candidates for treating delayed wound healing in diabetes due to the promotion of …

[HTML][HTML] Mesenchymal stem cell-derived extracellular vesicles: a potential therapy for diabetes mellitus and diabetic complications

F Sun, Y Sun, F Wu, W Xu, H Qian - Pharmaceutics, 2022 - mdpi.com
As a novel cell-free strategy, mesenchymal stem cell-derived extracellular vesicles (MSC-
EVs) inherit the therapeutic potential of donor cells, and are widely used for the treatment of …

Exosomes secreted by umbilical cord blood‐derived mesenchymal stem cell attenuate diabetes in mice

R Sharma, M Kumari, S Mishra… - Journal of diabetes …, 2021 - Wiley Online Library
Mesenchymal stem cell (MSC) therapy is an innovative approach in diabetes due to its
capacity to modulate tissue microenvironment and regeneration of glucose‐responsive …

[HTML][HTML] Therapeutic use of mesenchymal stem cell-derived exosomes: from basic science to clinics

CR Harrell, N Jovicic, V Djonov, V Volarevic - Pharmaceutics, 2020 - mdpi.com
Mesenchymal stem cells (MSC) are, due to their immunosuppressive and regenerative
properties, used as new therapeutic agents in cell-based therapy of inflammatory and …

Impaired bone regenerative effect of exosomes derived from bone marrow mesenchymal stem cells in type 1 diabetes

Y Zhu, Y Jia, Y Wang, J Xu, Y Chai - Stem Cells Translational …, 2019 - academic.oup.com
Stem cell-derived exosomes have exhibited promise for applications in tissue regeneration.
However, one major problem for stem cell-derived exosome therapies is identifying …

[HTML][HTML] Recent advances in the application of mesenchymal stem cell-derived exosomes for cardiovascular and neurodegenerative disease therapies

Z Yang, Y Li, Z Wang - Pharmaceutics, 2022 - mdpi.com
Exosomes are naturally occurring nanoscale vesicles that are released and received by
almost all cells in the body. Exosomes can be transferred between cells and contain various …