About 30% of depressed patients still suffer from considerable residual symptoms despite
treatment with established therapies such as antidepressants and psychotherapy. These …

Chronic Major depression is one of the most debilitating psychiatric disorders; 8-13% of
patients are treatment resistant. DBS has been applied to the following targets: Subcallosal …

Open-label studies of deep brain stimulation (DBS) for patients with treatment-resistant
depression (TRD) are promising: approximately 40% of patients lose at least half of their …

BACKGROUND: While most patients with depression respond to combinations of
pharmacotherapy, psychotherapy, and electroconvulsive therapy (ECT), there are patients …

Deep brain stimulation (DBS) is a new therapeutic approach for treatment-resistant
depression (TRD). There is a preliminary evidence of the efficacy and safety of DBS for TRD …

Introduction: Major depressive disorder (MDD) is the leading cause of years lost to disability
worldwide. Pharmacotherapy and psychotherapy are effective treatments in most depressive …

Purpose Deep brain stimulation (DBS) is a relatively new and still experimental treatment
modality for treatment-resistant depression (TRD). There is preliminary evidence that …

Deep brain stimulation (DBS) as a putative approach for treatment-resistant depression
(TRD) has now been researched for about a decade. Several uncontrolled studies—all in …

It is estimated that one-third of patients with depression show a lack of adequate response to
different pharmacological and non-pharmacological interventions, including …

High-frequency deep brain stimulation (DBS) represents a major stake for treatment for
treatment-resistant depression (TRD). We describe a preliminary trial of DBS of two potential …