The use of peptides as therapeutics is experiencing renewed enthusiasm owing to
advances in delivery, stability and design. Moreover, there is a growing emphasis on the use …

With recent advances in the design and delivery of peptide-based therapeutics there has
been a growing interest in the use of peptides in vaccine design. Moreover, functional …

Progress made in peptide-based vaccinations to induce T-cell-dependent immune
responses against cancer has invigorated the search for optimal vaccine modalities. Design …

Conventional vaccine strategies have been highly efficacious for several decades in
reducing mortality and morbidity due to infectious diseases. The bane of conventional …

Vaccination is a cost-effective approach to prevent, treat, and eradicate infectious diseases
and cancer. Classical whole-organism vaccines may have several pitfalls such as the …

Soon after it was realized that T-cells recognize their target antigens as small protein
fragments or peptides presented by MHC molecules at the cell surface, these peptide …

Vaccines have had a profound impact on the management and prevention of infectious
disease. In addition, the development of vaccines against chronic diseases has attracted …

This review discusses peptide epitopes used as antigens in the development of vaccines in
clinical trials as well as future vaccine candidates. It covers peptides used in potential …

Highlights•The recent findings in basic immunology revisit the use of peptide vaccine for
cancer.•Peptide size, formulation and delivery route are critical for peptide vaccine …

Highlights•Peptide cancer vaccines are safe, but have low therapeutic effect.•New epitopes
are being discovered through genomics, peptidomics, and bioinformatics.•High throughput …