Ovarian steroids, stem cells and uterine leiomyoma: therapeutic implications
MB Moravek, P Yin, M Ono, JS Coon V… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND Uterine leiomyoma is the most common benign tumor in women and is
thought to arise from the clonal expansion of a single myometrial smooth muscle cell …
thought to arise from the clonal expansion of a single myometrial smooth muscle cell …
Uterine leiomyoma stem cells: linking progesterone to growth
SE Bulun, MB Moravek, P Yin, M Ono… - Seminars in …, 2015 - thieme-connect.com
Uterine leiomyomas (fibroids) represent the most common class of benign tumors in women.
Multiple leiomyomas usually arise from the uterus of a symptomatic woman. These tumors …
Multiple leiomyomas usually arise from the uterus of a symptomatic woman. These tumors …
Treatment strategies for uterine leiomyoma: the role of hormonal modulation
JD Cook, CL Walker - Seminars in reproductive medicine, 2004 - thieme-connect.com
Uterine leiomyomas are the most common gynecological tumors and are a significant health
concern for many women. Although the exact etiology of these tumors is unknown …
concern for many women. Although the exact etiology of these tumors is unknown …
The role of progesterone signaling in the pathogenesis of uterine leiomyoma
JJ Kim, EC Sefton - Molecular and cellular endocrinology, 2012 - Elsevier
Uterine leiomyomas are benign tumors that originate from the myometrium. Evidence points
to ovarian steroid hormones, in particular, progesterone as major promoters of leiomyoma …
to ovarian steroid hormones, in particular, progesterone as major promoters of leiomyoma …
Progesterone is essential for maintenance and growth of uterine leiomyoma
H Ishikawa, K Ishi, VA Serna, R Kakazu… - …, 2010 - academic.oup.com
Uterine leiomyomata (ULs) represent the most common tumor in women and can cause
abnormal uterine bleeding, large pelvic masses, and recurrent pregnancy loss. Although the …
abnormal uterine bleeding, large pelvic masses, and recurrent pregnancy loss. Although the …
Effects of progesterone on uterine leiomyoma growth and apoptosis
T Maruo, H Matsuo, T Samoto, Y Shimomura… - Steroids, 2000 - Elsevier
Uterine leiomyomas appear during the reproductive years and regress after menopause,
indicating the ovarian steroid-dependent growth potential. Recently we have found that the …
indicating the ovarian steroid-dependent growth potential. Recently we have found that the …
Uterine leiomyoma: available medical treatments and new possible therapeutic options
Context: Uterine leiomyomas (fibroids or myomas) are benign tumors of the uterus and are
clinically apparent in up to 25% of reproductive-age women. Heavy or abnormal uterine …
clinically apparent in up to 25% of reproductive-age women. Heavy or abnormal uterine …
[HTML][HTML] Role of stem cells in human uterine leiomyoma growth
M Ono, W Qiang, VA Serna, P Yin, JS Coon, A Navarro… - PloS one, 2012 - journals.plos.org
Background Uterine leiomyoma is the most common benign tumor in reproductive-age
women. Each leiomyoma is thought to be a benign monoclonal tumor arising from a single …
women. Each leiomyoma is thought to be a benign monoclonal tumor arising from a single …
Steroid hormones and leiomyomas
Uterine leiomyomas or fibroids are benign, hormonally responsive, smooth muscle tumors
that have been reported to affect 20% to 40% of premenopausal women making them the …
that have been reported to affect 20% to 40% of premenopausal women making them the …
Sex steroidal regulation of uterine leiomyoma growth and apoptosis
T Maruo, N Ohara, J Wang… - Human reproduction …, 2004 - academic.oup.com
Uterine leiomyomas develop during the reproductive years and regress after menopause,
indicating ovarian steroid‐dependent growth potential. Although the clinical and …
indicating ovarian steroid‐dependent growth potential. Although the clinical and …
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