Early-life exposure to testosterone programs the hypothalamic melanocortin system

K Nohara, Y Zhang, RS Waraich, A Laque… - …, 2011 - academic.oup.com
In mammals, males consume more food, which is considered a masculinized behavior, but
the underlying mechanism of this sex-specific feeding behavior is unknown. In mice …

[HTML][HTML] Estrogenic action in stress-induced neuroendocrine regulation of energy homeostasis

KN Krolick, H Shi - Cells, 2022 - mdpi.com
Estrogens are among important contributing factors to many sex differences in
neuroendocrine regulation of energy homeostasis induced by stress. Research in this field …

The effects of estrogens on neural circuits that control temperature

Z Zhang, JR DiVittorio, AM Joseph, SM Correa - Endocrinology, 2021 - academic.oup.com
Declining and variable levels of estrogens around the time of menopause are associated
with a suite of metabolic, vascular, and neuroendocrine changes. The archetypal adverse …

[HTML][HTML] An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females

SM Correa, DW Newstrom, JP Warne, P Flandin… - Cell reports, 2015 - cell.com
Estrogen-receptor alpha (ERα) neurons in the ventrolateral region of the ventromedial
hypothalamus (VMH VL) control an array of sex-specific responses to maximize reproductive …

FRI288 Single-Cell Transcriptomics Identifies Pituitary Gland Cell Type Population Changes In Diet Induced Obesity

RE Ruggiero-Ruff, B Le, N Lainez… - Journal of the Endocrine …, 2023 - academic.oup.com
Abstract Disclosure: RE Ruggiero-Ruff: None. B. Le: None. N. Lainez: None. D. Coss: None.
Obesity is a worldwide growing public health concern, with a current prevalence of 43% in …

Maternal high fat diet in lactation impacts hypothalamic neurogenesis and neurotrophic development, leading to later life susceptibility to obesity in male but not …

Y Xu, D Yang, L Wang, E Król, M Mazidi, L Li… - Advanced …, 2023 - Wiley Online Library
Early life nutrition can reprogram development and exert long‐term consequences on body
weight regulation. In mice, maternal high‐fat diet (HFD) during lactation predisposed male …

An estrogen-sensitive hypothalamus-midbrain neural circuit controls thermogenesis and physical activity

H Ye, B Feng, C Wang, K Saito, Y Yang, L Ibrahimi… - Science …, 2022 - science.org
Estrogen receptor–α (ERα) expressed by neurons in the ventrolateral subdivision of the
ventromedial hypothalamic nucleus (ERαvlVMH) regulates body weight in females, but the …

Nutrient-sensing mechanisms in hypothalamic cell models: neuropeptide regulation and neuroinflammation in male-and female-derived cell lines

N Loganathan, DD Belsham - American Journal of …, 2016 - journals.physiology.org
The hypothalamus is responsible for the control of many of our physiological responses,
including energy homeostasis. Of interest, there are a number of instances of sexual …

[PDF][PDF] Regulation of body weight and metabolism by tanycyte-derived neurogenesis in young adult mice

S Blackshaw, DA Lee, T Pak, S Yoo - Stem Cells in …, 2016 - library.oapen.org
The hypothalamus controls many homeostatic and instinctive physiological processes,
including the sleep-wake cycle, food intake, and sexually dimorphic behaviors. These …

[HTML][HTML] Dietary and sex-specific factors regulate hypothalamic neurogenesis in young adult mice

DA Lee, S Yoo, T Pak, J Salvatierra, E Velarde… - Frontiers in …, 2014 - frontiersin.org
The hypothalamus is the central regulator of a broad range of homeostatic and instinctive
physiological processes, such as the sleep-wake cycle, food intake, and sexually dimorphic …