Adenosine A2A receptors facilitate 45Ca2+ uptake through class A calcium channels in rat hippocampal CA3 but not CA1 synaptosomes

ML Gonçalves, RA Cunha, JA Ribeiro - Neuroscience letters, 1997 - Elsevier
In the hippocampus, the neuromodulatory role of adenosine depends on a balance between
inhibitory A1 responses and facilitatory A2A responses. Since the presynaptic effects of …

Adenosine A2 receptor activation facilitates 45Ca2+ uptake by rat brain synaptosomes

ML Gonçalves, JA Ribeiro - European journal of pharmacology, 1996 - Elsevier
Adenosine has been shown to increase the release of neurotransmitters by stimulation of
adenosine A2 receptors. This effect probably depends on Ca2+ entry into presynaptic nerve …

A1 adenosine receptors differentially regulate the N-methyl-D-aspartate and non-N-methyl-D-aspartate receptor-mediated components of hippocampal excitatory …

A Klishin, N Lozovaya, O Krishtal - Neuroscience, 1995 - Elsevier
A1 adenosine receptors efficiently modulate the excitatory synaptic transmission in
hippocampus. Here we report that in addition to previously known modulatory action on the …

Activation of hippocampal adenosine A3 receptors produces a desensitization of A1 receptor-mediated responses in rat hippocampus

TV Dunwiddie, L Diao, HO Kim, JL Jiang… - Journal of …, 1997 - Soc Neuroscience
The adenosine A3 receptor is expressed in brain, but the consequences of activation of this
receptor on electrophysiological activity are unknown. We have characterized the actions of …

Adenosine A2A receptor facilitation of hippocampal synaptic transmission is dependent on tonic A1 receptor inhibition

LV Lopes, RA Cunha, B Kull, BB Fredholm, JA Ribeiro - Neuroscience, 2002 - Elsevier
Adenosine tonically inhibits synaptic transmission through actions at A1 receptors. It also
facilitates synaptic transmission, but it is unclear if this facilitation results from pre-and/or …

Adenosine A2A receptor facilitation of synaptic transmission in the CA1 area of the rat hippocampus requires protein kinase C but not protein kinase A activation

RA Cunha, JA Ribeiro - Neuroscience letters, 2000 - Elsevier
Adenosine is a neuromodulator in the hippocampus acting mainly via inhibitory A1 receptors
but also via facilitatory A2A receptors. We now investigated the transducing system operated …

Adenosine A3 receptors potentiate hippocampal calcium current by a PKA-dependent/PKC-independent pathway

KM Fleming, DJ Mogul - Neuropharmacology, 1997 - Elsevier
The modulation of high-threshold Ca current (ICa) by adenosine receptors was studied
using the voltage clamp method on acutely dissociated guinea pig hippocampal CA3 …

Adenosine A3 receptors in the rat hippocampus: Lack of interaction with A1 receptors

LV Lopes, N Rebola, AR Costenla… - Drug development …, 2003 - Wiley Online Library
Adenosine acts as a neuromodulator in the hippocampus essentially through activation of
inhibitory A1 receptors. Using single‐cell PCR analysis, we found that CA1 pyramidal cells …

High level of adenosine A1 receptor-like immunoreactivity in the CA2/CA3a region of the adult rat hippocampus

T Ochiishi, Y Saitoh, A Yukawa, M Saji, Y Ren, T Shirao… - Neuroscience, 1999 - Elsevier
We describe the immunocytochemical distribution of adenosine A1 receptors in the rat
hippocampus. Adenosine A1 receptor-like immunoreactivity was seen on the cell soma and …

Inhibition of N-, P/Q-and other types of Ca2+ channels in rat hippocampal nerve terminals by the adenosine A1 receptor

AF Ambrósio, JO Malva, AP Carvalho… - European journal of …, 1997 - Elsevier
The effects of the adenosine A1 receptor agonist, N6-cyclopentyladenosine (CPA), on both
the increase in intracellular free Ca2+ concentration ([Ca2+] i) and on the release of …