PlGF immunological impact during pregnancy

L Albonici, M Benvenuto, C Focaccetti, L Cifaldi… - International Journal of …, 2020 - mdpi.com
During pregnancy, the mother's immune system has to tolerate the persistence of paternal
alloantigens without affecting the anti-infectious immune response. Consequently, several …

Placental growth factor (PlGF) as an angiogenic/inflammatory switcher: lesson from early pregnancy losses

HR Nejabati, Z Latifi, T Ghasemnejad… - Gynecological …, 2017 - Taylor & Francis
Placental growth factor (PlGF) is an angiogenic factor which belongs to vascular endothelial
growth factor (VEGF) family. In addition to the angiogenic function of PlGF, in some …

Multifaceted role of the placental growth factor (PlGF) in the antitumor immune response and cancer progression

L Albonici, MG Giganti, A Modesti, V Manzari… - International Journal of …, 2019 - mdpi.com
The sharing of molecules function that affects both tumor growth and neoangiogenesis with
cells of the immune system creates a mutual interplay that impairs the host's immune …

Placental growth factor down-regulates type 1 T helper immune response by modulating the function of dendritic cells

YL Lin, YC Liang, BL Chiang - Journal of Leucocyte Biology, 2007 - academic.oup.com
Placental growth factor (PlGF) belongs to the vascular endothelial growth factor (VEGF)
family and represents a key regulator of angiogenic events in development and pathologic …

Mechanism of monocyte activation and expression of proinflammatory cytochemokines by placenta growth factor

SK Selvaraj, RK Giri, N Perelman, C Johnson, P Malik… - Blood, 2003 - ashpublications.org
Monocytes from patients with sickle cell disease (SCD) are in an activated state. However,
the mechanism of activation of monocytes in SCD is not known. Our studies showed that …

Role of placenta growth factor in cancer and inflammation

KJ Kim, CS Cho, WU Kim - Experimental & molecular medicine, 2012 - nature.com
Accumulating evidences have documented that angiogenesis is closely linked to
inflammation and regulators of angiogenesis play key roles in various inflammatory …

An insight into the placental growth factor (PlGf)/angii axis in Covid-19: a detrimental intersection

HM Al-Kuraishy, AI Al-Gareeb… - Biotechnology and …, 2022 - Taylor & Francis
ABSTRACT Coronavirus disease 2019 (Covid-19) is a recent and current infectious
pandemic caused by severe acute respiratory syndrome coronavirus type 2 (SARS-CoV-2) …

Placental growth factor and pre-eclampsia

K Chau, A Hennessy, A Makris - Journal of human hypertension, 2017 - nature.com
Placental growth factor (PlGF) is an increasingly important molecule in the prediction,
diagnosis and treatment of pre-eclampsia. It has pro-angiogenic effects on the feto-placental …

Placental growth factor and cardiac inflammation

D Carnevale, G Lembo - Trends in cardiovascular medicine, 2012 - Elsevier
Placental growth factor (PlGF) belongs to the vascular endothelial growth factor family and is
one of the most interesting candidates as an “angiogenic cytokine,” capable of not only …

Placental and maternal sFlt1/PlGF expression in gestational diabetes mellitus

AM Nuzzo, D Giuffrida, L Moretti, P Re, G Grassi… - Scientific Reports, 2021 - nature.com
Gestational diabetes mellitus (GDM) and preeclampsia (PE) are both characterized by
endothelial dysfunction and GDM women have higher incidence of PE. The placenta plays a …