A successful candidate for oral drug delivery needs to possess adequate solubility and
dissolution rate to elicit its therapeutic action. Extensive research is being carried out to …

Amorphous systems have been applied effectively in the pharmaceutical industry for a
number of commercial and developmental products, although they are still considered a …

The use of amorphous solid dispersions is an interesting strategy to increase the
bioavailability of poorly soluble drugs by improving their rate and extent of dissolution. Lack …

Amorphous solid dispersions (ASDs) are an attractive option to improve the bioavailability of
poorly water-soluble compounds. However, the material attributes of ASDs can present …

Amorphous solid dispersions (ASDs) are commonly used in the pharmaceutical industry to
improve the dissolution and bioavailability of poorly water-soluble drugs. Hot melt extrusion …

Solubility limited bioavailability is one of the crucial parameters that affect the formulation
development of the new chemical entities. Thus the major constraint in the pharmaceutical …

The current study aimed to see the effects of poloxamer P407 on the dissolution
performance of hydroxypropyl methylcellulose acetate succinate (AquaSolve™ HPMC-AS …

Amorphous solid dispersion (ASD) is one of the most effective approaches for delivering
poorly soluble drugs. In ASDs, polymeric materials serve as the carriers in which the drugs …

Out of many, one of the most promising strategies to improve the oral bioavailability of poorly
water-soluble drugs is to develop amorphous solid dispersions. Reduction in drug particle …

The development of amorphous solid dispersions (ASDs) is one way to overcome the
bioavailability challenges of poorly water-soluble active pharmaceutical ingredients (APIs) …