Lineage-specific chimaerism quantification after T-cell depleted peripheral blood stem cell transplantation
Patients that receive a T-cell depleted (TCD) hematopoietic stem cell transplantation (SCT)
show higher risk of graft failure/rejection and of disease relapse than those that receive …
show higher risk of graft failure/rejection and of disease relapse than those that receive …
Early recipient chimerism testing in the T-and NK-cell lineages for risk assessment of graft rejection in pediatric patients undergoing allogeneic stem cell …
S Breuer, S Preuner, G Fritsch, H Daxberger, M Koenig… - Leukemia, 2012 - nature.com
Timely diagnosis of impending graft rejection is crucial for effective therapeutic intervention
after allogeneic hematopoietic stem cell transplantation (SCT). We have investigated the …
after allogeneic hematopoietic stem cell transplantation (SCT). We have investigated the …
Validation of next-generation sequencing-based chimerism testing for accurate detection and monitoring of engraftment in hematopoietic stem cell transplantation
P Kakodkar, Y Zhao, H Pan, F Wu, T Pearce… - Frontiers in …, 2023 - frontiersin.org
Allogenic hematopoietic stem cell transplantation (allo-HSCT) is a life-saving treatment for
various hematological disorders. The success of allo-HSCT depends on the engraftment of …
various hematological disorders. The success of allo-HSCT depends on the engraftment of …
Monitoring minimal residual/relapsing disease after allogeneic haematopoietic stem cell transplantation in adult patients with acute lymphoblastic leukaemia
K Wethmar, S Matern, E Eßeling, L Angenendt… - Bone Marrow …, 2020 - nature.com
Relapse after allogeneic haematopoietic stem cell transplantation (SCT) is a major cause of
death in patients with acute lymphoblastic leukaemia (ALL). Here, we retrospectively …
death in patients with acute lymphoblastic leukaemia (ALL). Here, we retrospectively …
Increasing mixed chimerism is an important prognostic factor for unfavorable outcome in children with acute lymphoblastic leukemia after allogeneic stem-cell …
P Bader, H Kreyenberg, W Hoelle… - Journal of clinical …, 2004 - ascopubs.org
Purpose We recently reported that children with acute leukemias who show increasing
mixed chimerism (MC) after allogeneic stem-cell transplantation have a significantly …
mixed chimerism (MC) after allogeneic stem-cell transplantation have a significantly …
Impact of early chimerism status on clinical outcome in children with acute lymphoblastic leukaemia after haematopoietic stem cell transplantation
M Lejman, A Zaucha-Prażmo, J Zawitkowska… - BMC cancer, 2019 - Springer
Background The significance of very early chimerism assessment before day+ 28, which is
considered the moment of engraftment, is still unclear. In this retrospective study, we …
considered the moment of engraftment, is still unclear. In this retrospective study, we …
Use of chimerism analysis after allogeneic stem cell transplantation: Belgian guidelines and review of the current literature
A Delie, A Verlinden, K Beel, D Deeren… - Acta Clinica …, 2021 - Taylor & Francis
Background: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative
treatment option in both adult and pediatric patients with malignant and non-malignant …
treatment option in both adult and pediatric patients with malignant and non-malignant …
Kinetics of chimerism during the early post-transplant period in pediatric patients with malignant and non-malignant hematologic disorders: implications for timely …
J Dubovsky, H Daxberger, G Fritsch, D Printz, C Peters… - Leukemia, 1999 - nature.com
The monitoring of chimerism by PCR has become a routine diagnostic approach in patients
after allogeneic bone marrow or peripheral blood stem cell transplantation. Nevertheless, a …
after allogeneic bone marrow or peripheral blood stem cell transplantation. Nevertheless, a …
[HTML][HTML] NCI first international workshop on the biology, prevention, and treatment of relapse after allogeneic hematopoietic stem cell transplantation: report from the …
Relapse has become the major cause of treatment failure after allogeneic stem cell
transplantation. Outcome of patients with clinical relapse after transplantation generally …
transplantation. Outcome of patients with clinical relapse after transplantation generally …
Evaluation of immunomodulatory treatment based on conventional and lineage-specific chimerism analysis in patients with myeloid malignancies after myeloablative …
R Zeiser, A Spyridonidis, R Wäsch, G Ihorst, C Grüllich… - Leukemia, 2005 - nature.com
Both conventional chimerism analysis (CCA) and lineage-specific chimerism analysis (LCA)
have potential pitfalls as diagnostic means for the detection of minimal residual disease after …
have potential pitfalls as diagnostic means for the detection of minimal residual disease after …