Progress in chimerism analysis in childhood malignancies–the dilemma of biostatistical considerations and ethical implications
In recent years, considerable progress has been made in the analysis of hematopoietic
chimerism after allogeneic stem cell transplantation (SCT). The introduction of serial and …
chimerism after allogeneic stem cell transplantation (SCT). The introduction of serial and …
Debate round-table: comments concerning chimerism studies
M Gonzalez, R Lopez-Perez, R Garcia-Sanz… - Leukemia, 2001 - nature.com
Allogeneic stem cell transplantation (allo-SCT) is the treatment of choice for many patients
with hematological malignancies, as well as some non-malignant hematological disorders …
with hematological malignancies, as well as some non-malignant hematological disorders …
Intensive monitoring of minimal residual disease and chimerism after allogeneic hematopoietic stem cell transplantation for acute leukemia in children
T Pincez, R Santiago, H Bittencourt, I Louis… - Bone Marrow …, 2021 - nature.com
Posttransplant leukemia detection before overt relapse is key to the success of
immunotherapeutic interventions, as they are more efficient when leukemia burden is low …
immunotherapeutic interventions, as they are more efficient when leukemia burden is low …
Hematopoietic chimerism after allogeneic stem cell transplantation: a comparison of quantitative analysis by automated DNA sizing and fluorescent in situ …
J Jółkowska, A Pieczonka, T Strabel, D Boruczkowski… - BMC Hematology, 2005 - Springer
Background Allogeneic hematopoietic stem cell transplantation (allo-HSCT) is performed
mainly in patients with high-risk or advanced hematologic malignancies and congenital or …
mainly in patients with high-risk or advanced hematologic malignancies and congenital or …
[HTML][HTML] Prognostic utility of routine chimerism testing at 2 to 6 months after allogeneic hematopoietic cell transplantation
GI Mossallam, AM Kamel, B Storer, PJ Martin - Biology of Blood and …, 2009 - Elsevier
The utility of routine chimerism analysis as a prognostic indicator of subsequent outcomes
after allogeneic hematopoietic cell transplantation (HCT) with myeloablative conditioning …
after allogeneic hematopoietic cell transplantation (HCT) with myeloablative conditioning …
[HTML][HTML] Achievement of early complete donor chimerism in CD25+-activated leukocytes is a strong predictor of the development of graft-versus-host-disease after …
C Martínez-Laperche, V Noriega, M Kwon… - Experimental …, 2015 - Elsevier
Chimerism dynamics in bone marrow, peripheral blood (PB), and T lymphocytes (TL) has
been associated with the development of various complications after allogeneic stem-cell …
been associated with the development of various complications after allogeneic stem-cell …
Mixed T cell lineage chimerism in acute leukemia/MDS using pre-emptive donor lymphocyte infusion strategy—Is it prognostic?—a single-center retrospective study
V Sheth, V Potter, H de Lavallade, S Gandhi… - Blood Cancer …, 2021 - nature.com
Pre-emptive DLI (pDLI) is an effective strategy in lowering the risk of relapse without
significantly increasing the risk of graft-versus-host disease (GVHD) in the case of T cell …
significantly increasing the risk of graft-versus-host disease (GVHD) in the case of T cell …
Chimerism analysis following nonmyeloablative stem cell transplantation
T Lion, F Watzinger - Myeloid Leukemia: Methods and Protocols, 2006 - Springer
Molecular monitoring of hematopoietic chimerism has become a routine diagnostic
approach in patients after allogeneic stem cell transplantation. Chimerism testing permits the …
approach in patients after allogeneic stem cell transplantation. Chimerism testing permits the …
Delayed attainment of full donor chimaerism following alemtuzumab‐based reduced‐intensity conditioning haematopoeitic stem cell transplantation for acute myeloid …
ZY Lim, L Pearce, AY Ho, L Barber… - British journal of …, 2007 - Wiley Online Library
This prospective study evaluated the kinetics of lymphoid (CD3) engraftment in 110 patients
with acute myeloid leukaemia (AML) and myelodysplastic syndromes (MDS) after allogeneic …
with acute myeloid leukaemia (AML) and myelodysplastic syndromes (MDS) after allogeneic …
Reduced intensity conditioning and prophylactic DLI can cure patients with high-risk acute leukaemias if complete donor chimerism can be achieved
G Massenkeil, M Nagy, M Lawang, O Rosen… - Bone marrow …, 2003 - nature.com
23 patients with ALL (n= 9) and AML (n= 14) underwent nonmyeloablative stem cell
transplantation (NST) from an HLA-identical donor after conditioning with fludarabine (180 …
transplantation (NST) from an HLA-identical donor after conditioning with fludarabine (180 …