Autism spectrum disorder is a neurodevelopmental condition characterized by impaired
social communication and repetitive behaviors. Changes in the number of specific cell types …

The cerebral cortex presents with alterations in the number of specific cell types in autism
spectrum disorder (ASD). Astrocytes have many functions in the brain including a role in …

Background Autism involves early brain overgrowth and dysfunction, which is most strongly
evident in the prefrontal cortex. As assessed on pathological analysis, an excess of neurons …

Although the neurobiology of autism has been studied for more than two decades, the
majority of these studies have examined brain structure 10, 20, or more years after the onset …

The most replicated finding in autism neuroanatomy—a tendency to unusually large brains—
has seemed paradoxical in relation to the specificity of the abnormalities in three behavioral …

Microglial activation and alterations in neuron number have been reported in autism.
However, it is unknown whether microglial activation in the disorder includes a neuron …

Autism is a neurodevelopmental disorder characterized by deficits in social interaction and
social communication, as well as by the presence of repetitive and stereotyped behaviors …

An interneuron alteration has been proposed as a source for the modified balance of
excitation/inhibition in the cerebral cortex in autism. We previously demonstrated a …

The functional integrity of the neocortex depends upon proper numbers of excitatory and
inhibitory neurons; however, the consequences of dysregulated neuronal production during …

A distinct pathology for autism spectrum disorder (ASD) remains elusive. Human and animal
studies have focused on investigating the role of neurons in ASD. However, recent studies …