Pharmacological and endocrine profiles of gestodene.

J Spona, J Huber - International Journal of Fertility, 1987 - europepmc.org
Efforts to minimize oral contraceptive side effects have focused on the use of new dosage
schemes and the synthesis of new steroids that can be used in safer, low-dose formulations …

Inhibition of ovulation by a triphasic gestodene-containing oral contraceptive

J Spona, U Lachnit-Fixson, B Düsterberg… - Advances in …, 1993 - Springer
The minimal effective dose of gestodene for inhibition of ovulation was studied in 30 female
volunteers. Daily doses of 10 μg to 50 μg gestodene were given orally for 21 days. A control …

Gestodene: a review of its pharmacology, efficacy and tolerability in combined contraceptive preparations

MI Wilde, JA Balfour - Drugs, 1995 - Springer
The newer progestogens gestodene, desogestrel and norgestimate were developed in an
attempt to produce agents with more selective progestational activity that would improve …

Inhibition of ovulation by low-dose monophasic contraceptive containing gestodene

K Thomas, L Vankrieken - American journal of obstetrics and gynecology, 1990 - Elsevier
Ovulation inhibition by the monophasic oral contraceptive containing 75 μg of gestodene
and 30 wg of ethinyl estradiol was evaluated in 25 healthy volunteers for five cycles: a …

Pharmacokinetics of gestodene and ethinyl estradiol after oral administration of a monophasic contraceptive

U Täuber, W Kuhnz, M Hümpel - American journal of obstetrics and …, 1990 - Elsevier
The pharmacokinetic and protein-binding properties of gestodene and ethinyl estradiol have
been investigated after single and multiple dosing in several studies in 83 healthy, young …

Clinical and metabolic effects of gestodene and levonorgestrel.

T Rabe, B Runnebaum, M Kohlmeier… - … journal of fertility, 1987 - europepmc.org
The new low-dose combination oral contraceptive (OC) containing 75 micrograms of the
new progestogen gestodene (GTD) plus 30 micrograms ethinyl estradiol (EE) was clinically …

Inhibition of ovulation by a new low-dose monophasic contraceptive containing gestodene.

KH Thomas, L Vankrieken - International journal of fertility, 1989 - europepmc.org
Twenty-five healthy women volunteers were selected to evaluate ovulation inhibition by a
monophasic oral contraceptive preparation containing 75 micrograms gestodene and 30 …

Dose finding in a low-dose 21-day combined oral contraceptive containing gestodene

F Lüdicke, H Sullivan, J Spona, M Elstein - Contraception, 2001 - Elsevier
An open label, non-comparative study was carried out in 22 women over a total of five
cycles. After an untreated cycle, oral administration of 20 μg ethinyl estradiol (EE) with 50 μg …

Gestodene: a novel synthetic progestin—characterization of binding to receptor and serum proteins

K Pollow, M Juchem, HJ Grill, W Elger, S Beier… - Contraception, 1989 - Elsevier
Abstract Gestodene, 17α-ethinyl-13-ethyl-17β-hydroxy-4, 15-gonadien-3-one, is a new
orally active progestational agent, which is available for clinical use in oral contraceptives …

Clinical experience with a low-dose oral contraceptive containing gestodene.

B Düsterberg, K Brill - … in Contraception: the Official Journal of the …, 1990 - europepmc.org
The monophasic combination preparation containing 30 micrograms ethinyl estradiol and
75 micrograms gestodene was tested for contraceptive reliability, cycle control and …